There are 6 ways to get from Port Saint Lucie to Indiana by car, plane, bus (Flixbus), bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly
best- Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Indianapolis (IND)plane SFB - IND
5h 52m$136–637Bus (Flixbus)
- Take the bus from Port St Lucie to Atlanta Bus Stationbus FlixBus N2401
- Take the bus from Atlanta Bus Station to Indianapolisbus FlixBus 2512
23h$196–296Drive 1,039.9 mi
- Drive from Port Saint Lucie to Indianapoliscar 1,039.9 mi
18h 21m$190–275Bus to Orlando, fly
- Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus
- Fly from Orlando (MCO) to Indianapolis (IND)plane MCO - IND
7h 42m$206–795Bus to Fort Lauderdale–Hollywood International Airport, fly
- Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Indianapolis (IND)plane FLL - IND
7h 12m$533–1,245Bus via Pembroke Pines
- Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus
- Take the bus from Hollywood Sheridan Trirail Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus
30h 44m$215–348
Port Saint Lucie to Indiana by bus
Comparing Your Travel Options
The cheapest way to get from Port Saint Lucie to Indiana is to drive which costs $190 - $280 and takes 18h 21m.
The fastest way to get from Port Saint Lucie to Indiana is to drive and fly which takes 5h 52m and costs $130 - $650.
No, there is no direct bus from Port Saint Lucie to Indiana. However, there are services departing from Port St Lucie and arriving at Indianapolis via Atlanta Bus Station. The journey, including transfers, takes approximately 23h.
The distance between Port Saint Lucie and Indiana is 960 miles. The road distance is 1045.9 miles.
The best way to get from Port Saint Lucie to Indiana without a car is to bus which takes 23h and costs $190 - $300.
It takes approximately 5h 52m to get from Port Saint Lucie to Indiana, including transfers.
Port Saint Lucie to Indiana bus services, operated by Flixbus USA, depart from Port St Lucie station.
Port Saint Lucie to Indiana bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Port Saint Lucie to Indiana is 1046 miles. It takes approximately 18h 21m to drive from Port Saint Lucie to Indiana.
There are 885+ hotels available in Indiana.
What companies run services between Port Saint Lucie, FL, USA and Indiana, USA?
You can take a vehicle from Port Saint Lucie to Indianapolis via Port St Lucie and Atlanta Bus Station in around 23h.
- Website
- southwest.com
Flights from Orlando to Indianapolis
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $110–600
Flights from Fort Lauderdale–Hollywood International Airport to Indianapolis
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $140–750
Flights from Fort Lauderdale–Hollywood International Airport to Indianapolis via Orlando
- Ave. Duration
- 4h 20m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Fort Lauderdale–Hollywood International Airport to Indianapolis via Tampa
- Ave. Duration
- 4h 25m
- When
- Saturday
- Estimated price
- $140–750
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Port St Lucie to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Indianapolis
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
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