What is the cheapest way to get from Port Saint Lucie to Key West?

The cheapest way to get from Port Saint Lucie to Key West is to drive which costs $50 - $75 and takes 5h 24m.

What is the fastest way to get from Port Saint Lucie to Key West?

The fastest way to get from Port Saint Lucie to Key West is to drive and fly which takes 3h 53m and costs $70 - $300.

Is there a direct bus between Port Saint Lucie and Key West?

No, there is no direct bus from Port Saint Lucie to Key West. However, there are services departing from Fort Pierce and arriving at N Roosevelt & 3rd Street via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 9h 17m.

How far is it from Port Saint Lucie to Key West?

The distance between Port Saint Lucie and Key West is 248 miles. The road distance is 274.3 miles.

How do I travel from Port Saint Lucie to Key West without a car?

The best way to get from Port Saint Lucie to Key West without a car is to bus which takes 9h 17m and costs $50 - $85.

How long does it take to get from Port Saint Lucie to Key West?

It takes approximately 4h 21m to get from Port Saint Lucie to Key West, including transfers.

Where do I catch the Port Saint Lucie to Key West bus from?

Port Saint Lucie to Key West bus services, operated by RedCoach, depart from Fort Pierce station.

Where does the Port Saint Lucie to Key West bus arrive?

Port Saint Lucie to Key West bus services, operated by RedCoach, arrive at Miami Airport station.

Can I drive from Port Saint Lucie to Key West?

Yes, the driving distance between Port Saint Lucie to Key West is 274 miles. It takes approximately 5h 24m to drive from Port Saint Lucie to Key West.

How do I get a bus ticket from Port Saint Lucie to Key West?

Book your Port Saint Lucie to Key West bus tickets online with Omio.

Where can I stay near Key West?

There are 874+ hotels available in Key West.

Port Saint Lucie to Key West - 7 ways to travel via train, bus, plane, and car

How to get fromPort Saint Lucie to Key West

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There are 7 ways to get from Port Saint Lucie to Key West by bus, plane, bus (Greyhound), car, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus to Miami International Airport, fly
best
1. Take the bus from Fort Pierce to Miami Airportbus
2. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane MIA - EYW
4h 21m
$69–253
Drive 272.7 mi
cheapest
1. Drive from Port Saint Lucie to Key Westcar 272.7 mi
5h 24m
$50–72
Bus
1. Take the bus from Fort Pierce to Miami Airportbus
2. Take the bus from Miami Airport Station to Big Pine Keybus
3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
9h 17m
$53–84
Bus, shuttle
1. Take the bus from Fort Pierce to Miami Airportbus Orlando–Miami / ...
2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle To the Keys
8h 21m
$203–244
Bus to Orlando, fly
1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus
2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
4h 30m
$106–717
Drive to Orlando Sanford, fly
1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar
2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
3h 53m
$70–298
Bus, train
1. Take the bus from Fort Pierce to Fort Lauderdale - Broward Blvd Park and Ridebus
2. Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
3. Take the bus from Miami Airport Station to Big Pine Keybus
4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
10h
$56–88

Port Saint Lucie to Key West by bus, tram, and foot

31Weekly Services

9h 17mAverage Duration

$53Cheapest Price

See schedules

Questions & Answers

Map of how to get from Port Saint Lucie to Key West.

Launch map view

Distance: 246.8 mi
Duration: 4h 21m

What companies run services between Port Saint Lucie, FL, USA and Key West, FL, USA?

You can take a bus from Fort Pierce to N Roosevelt & 3rd Street via Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 9h 17m.

Airlines

Train operators

Bus operators

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How to get fromPort Saint Lucie to Key Westby bus, plane, bus (Greyhound), car, shuttle, or train

There are 7 ways to get from Port Saint Lucie to Key West by bus, plane, bus (Greyhound), car, shuttle, or train

Bus to Miami International Airport, fly

Drive 272.7 mi

Bus

Bus, shuttle

Bus to Orlando, fly

Drive to Orlando Sanford, fly

Bus, train