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How to get fromPort Saint Lucie to Key West (Island)by bus, train, plane, bus (Greyhound), car, or shuttle

Find Transport to Key West (Island)

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There are 7 ways to get from Port Saint Lucie to Key West (Island) by bus, train, plane, bus (Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train to Miami International Airport, fly

    best
    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Take the train from Sheridan Street Station to Miami Airport Stationtrain train
    3. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    4h 48m
    $60–254

  2. Drive 272.7 mi

    cheapest
    1. Drive from Port Saint Lucie to Key Westcar car 272.7 mi
    5h 24m
    $50–72

  3. Bus

    1. Take the bus from Fort Pierce to Miami International Airportbus bus Orlando to Miami
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    9h
    $55–85

  4. Bus, shuttle

    1. Take the bus from Fort Pierce to Miami International Airportbus bus Orlando to Miami
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    8h 25m
    $202–240

  5. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h 30m
    $104–693

  6. Drive to Orlando Sanford, fly

    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 51m
    $59–285

  7. Bus to Tampa, fly

    1. Take the bus from Port St Lucie to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    7h 49m
    $133–489

Port Saint Lucie to Key West (Island) by bus and tram

Calendar14Weekly Services
Duration9hAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Key West (Island).ExpandLaunch map view
  • Distance: 242.9 mi
  • Duration: 4h 48m

What companies run services between Port Saint Lucie, FL, USA and Key West (Island), FL, USA?

You can take a bus from Fort Pierce to Key West Airport via Miami International Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 9h.

Airlines
Train operators
Bus operators

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