What is the cheapest way to get from Port Saint Lucie to Murrells Inlet?

The cheapest way to get from Port Saint Lucie to Murrells Inlet is to drive which costs $100 - $150 and takes 9h 48m.

What is the fastest way to get from Port Saint Lucie to Murrells Inlet?

The fastest way to get from Port Saint Lucie to Murrells Inlet is to bus and fly which takes 5h 38m and costs $210 - $550.

Is there a direct bus between Port Saint Lucie and Murrells Inlet?

No, there is no direct bus from Port Saint Lucie to Murrells Inlet station. However, there are services departing from SW Airoso Blvd & Crosstown Pkwy and arriving at Myrtle Beach Bus Station via Avenue D & N 8th St, Fort Pierce, Jacksonville and Sumter Bus Stop. The journey, including transfers, takes approximately 23h 7m.

How far is it from Port Saint Lucie to Murrells Inlet?

The distance between Port Saint Lucie and Murrells Inlet is 469 miles. The road distance is 554.2 miles.

How do I travel from Port Saint Lucie to Murrells Inlet without a car?

The best way to get from Port Saint Lucie to Murrells Inlet without a car is to bus and train which takes 16h and costs $190 - $380.

How long does it take to get from Port Saint Lucie to Murrells Inlet?

It takes approximately 6h 21m to get from Port Saint Lucie to Murrells Inlet, including transfers.

Where do I catch the Port Saint Lucie to Murrells Inlet bus from?

Port Saint Lucie to Murrells Inlet bus services, operated by Greyhound USA, depart from Fort Pierce station.

Where does the Port Saint Lucie to Murrells Inlet bus arrive?

Port Saint Lucie to Murrells Inlet bus services, operated by Greyhound USA, arrive at Jacksonville station.

Can I drive from Port Saint Lucie to Murrells Inlet?

Yes, the driving distance between Port Saint Lucie to Murrells Inlet is 554 miles. It takes approximately 9h 48m to drive from Port Saint Lucie to Murrells Inlet.

Where can I stay near Murrells Inlet?

There are 3291+ hotels available in Murrells Inlet.

Port Saint Lucie to Murrells Inlet - 8 ways to travel via train, taxi

How to get fromPort Saint Lucie to Murrells Inlet

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There are 8 ways to get from Port Saint Lucie to Murrells Inlet by taxi, plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Taxi to Vero Beach Municipal Airport, fly
best
1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi
2. Fly from Vero Beach Municipal Airport (VRB) to Myrtle Beach (MYR)plane VRB - MYR
6h 21m
$202–539
Drive 551 mi
cheapest
1. Drive from Port Saint Lucie to Murrells Inletcar 551 mi
9h 48m
$101–146
Bus, train
1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus
2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain
3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
16h
$196–373
Bus (Greyhound)
1. Take the bus from Fort Pierce to Jacksonvillebus
2. Take the bus from Jacksonville to Sumter Bus Stopbus
3. Take the bus from Sumter Bus Stop to Myrtle Beach Bus Stationbus
23h 7m
$148–272
Bus to Orlando, fly
1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus
2. Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
6h 11m
$174–343
Bus to Fort Lauderdale–Hollywood International Airport, fly
1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus
2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane FLL - MYR
5h 38m
$211–513
Bus to Tampa, fly
1. Take the bus from Port St Lucie to Tampa Bus Stationbus
2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
8h 30m
$182–479
Bus, train, drive
1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus 95
2. Take the train from West Palm Beach Amtrak Station to Kingstree Stationtrain
3. Drive from Kingstree Station to Murrells Inletcar
16h 21m
$224–456

Vero Beach Municipal Airport (VRB) to Myrtle Beach (MYR) flights

18Weekly Planes

7h 50mAverage Duration

$71Cheapest Price

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Questions & Answers

Map of how to get from Port Saint Lucie to Murrells Inlet.

Launch map view

Distance: 466.1 mi
Duration: 6h 21m

What companies run services between Port Saint Lucie, FL, USA and Murrells Inlet, SC, USA?

You can take a bus from SW Airoso Blvd & Crosstown Pkwy to Murrells Inlet via Avenue D & N 8th St, Wheeler Ter & Okeechobee Rd, Fort Pierce, Jacksonville, Sumter Bus Stop, and Myrtle Beach Bus Station in around 23h 7m.

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