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How to get fromPort Saint Lucie to Murrells Inletby taxi, plane, bus, train, or car

Find Transport to Murrells Inlet

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There are 7 ways to get from Port Saint Lucie to Murrells Inlet by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Myrtle Beach (MYR)plane plane VRB - MYR
    5h 8m
    $197–519

  2. Drive  551 mi

    cheapest
    1. Drive from Port Saint Lucie to Murrells Inletcar car 551 mi
    9h 48m
    $101–146

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    16h 11m
    $308–471

  4. Bus to Orlando, fly

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Myrtle Beach (MYR)plane plane MCO - MYR
    6h 11m
    $174–303

  5. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane plane FLL - MYR
    5h 43m
    $231–503

  6. Bus to Tampa, fly

    1. Take the bus from Port St Lucie to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    8h 30m
    $193–479

  7. Bus, train, drive

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus 95
    2. Take the train from West Palm Beach Amtrak Station to Kingstree Stationtrain train
    3. Drive from Kingstree Station to Murrells Inletcar car
    16h 21m
    $394–606

Vero Beach Municipal Airport (VRB) to Myrtle Beach (MYR) flights

Calendar13Weekly Planes
Duration5h 44mAverage Duration
Ticket$65Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Murrells Inlet.ExpandLaunch map view
  • Distance: 466.1 mi
  • Duration: 5h 8m

What companies run services between Port Saint Lucie, FL, USA and Murrells Inlet, SC, USA?

There is no direct connection from Port Saint Lucie to Murrells Inlet. However, you can take the taxi to Vero Beach Municipal Airport (VRB) airport, fly to Myrtle Beach (MYR), then take the taxi to Murrells Inlet. Alternatively, you can take a bus from Fort Pierce to Murrells Inlet via Kissimmee -1471 East Osceola Parkway, Osceola Pkwy Walmart, Pleasant St & Neptune Rd, Kissimmee Amtrak Station, Charleston Amtrak Station, Charleston Bus Station, and Myrtle Beach Bus Station in around 16h 11m.

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