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How to get fromPort Saint Lucie to Orangeburgby bus (Flixbus), bus, train, car, taxi, plane, or bus (Greyhound, Flixbus)

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There are 12 ways to get from Port Saint Lucie to Orangeburg by bus (Flixbus), bus, train, car, taxi, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Pierce to Orlandobus bus Miami to Orlando
    2. Take the bus from Orlando Bus Station to Orangeburgbus bus FlixBus 2433
    12h 5m
    $101–162

  2. Bus via Jacksonville

    cheapest
    1. Take the bus from Fort Pierce to Jacksonvillebus bus Greyhound US0710s
    2. Take the bus from Jacksonville to Orangeburgbus bus FlixBus 2433
    14h 4m
    $78–147

  3. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus Miami to Orlando
    2. Take the train from Kissimmee Amtrak Station to Denmark Amtrak Stationtrain train Floridian
    13h 19m
    $217–391

  4. Drive 471.4 mi

    1. Drive from Port Saint Lucie to Orangeburgcar car 471.4 mi
    8h 15m
    $86–125

  5. Taxi to Vero Beach Municipal Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    8h 35m
    $229–775

  6. Bus, train via North Charleston

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Orangeburgbus bus
    14h 41m
    $180–351

  7. Bus to President Donald J. Trump International Airport, fly to Charleston International Airport, bus

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS)plane plane PBI - CHS
    3. Take the bus from Charleston Bus Station to Orangeburgbus bus
    9h 23m
    $172–838

  8. Bus to Miami International Airport, fly to Savannah, train

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Savannah (SAV)plane plane MIA - SAV
    3. Take the train from Savannah Station to Denmark Amtrak Stationtrain train
    8h 37m
    $236–654

  9. Bus to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport, bus

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    3. Take the bus from Charleston Bus Station to Orangeburgbus bus
    9h 38m
    $223–1,177

  10. Bus to President Donald J. Trump International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charlotte Douglas International Airport (CLT)plane plane PBI - CLT
    3. Take the bus from Charlotte Bus Station to Orangeburgbus bus
    11h 5m
    $187–770

  11. Bus to Miami International Airport, fly to Charleston International Airport, bus

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Take the bus from Charleston Bus Station to Orangeburgbus bus
    10h 5m
    $555–1,078

  12. Bus to Orlando, fly to Charleston International Airport, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    3. Take the bus from Charleston Bus Station to Orangeburgbus bus
    10h 12m
    $121–327

Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT) flights

Calendar7Weekly Planes
Duration1h 58mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Orangeburg.ExpandLaunch map view
  • Distance: 516.2 mi
  • Duration: 12h 5m

What companies run services between Port Saint Lucie, FL, USA and Orangeburg, SC, USA?

You can take a bus from Fort Pierce to Orangeburg via L B Mcleod Rd & Gardenia Ave, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Orangeburg in around 12h 5m.

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