Rome2Rio

How to get fromPort Saint Lucie to Sienaby bus, plane, train, or taxi

Find Transport to Siena

See all options

There are 8 ways to get from Port Saint Lucie to Siena by bus, plane, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Miami International Airport, fly to Florence Peretola Airport, train

    best
    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Florence Peretola Airport (FLR)plane plane MIA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    18h 18m
    €480–905

  2. Bus to Orlando, fly to Pisa International Airport, train

    cheapest
    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Pisa International Airport (PSA)plane plane MCO - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    18h 16m
    €363–627

  3. Bus to Orlando, fly to Florence Peretola Airport, train

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Florence Peretola Airport (FLR)plane plane MCO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    18h 18m
    €409–968

  4. Bus to Miami International Airport, fly to Pisa International Airport, train

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Pisa International Airport (PSA)plane plane MIA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    18h 55m
    €374–964

  5. Bus to Orlando, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the bus from Fort Pierce to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane MCO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    19h 12m
    €396–643

  6. Bus to Miami International Airport, fly to Fiumicino International Airport, train

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Fiumicino International Airport (FCO)plane plane MIA - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    18h 46m
    €390–935

  7. Taxi to Vero Beach Municipal Airport, fly to Fiumicino International Airport, train

    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Fiumicino International Airport (FCO)plane plane VRB - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    18h 31m
    €453–1,145

  8. Bus to Miami International Airport, fly to Milano Malpensa Airport, train

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Milano Malpensa Airport (MXP)plane plane MIA - MXP
    3. Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain train
    4. Take the train from Milano P.Garibaldi to Firenze S.M.N.train train
    5. Take the train from Firenze S.M.N. to Sienatrain train
    19h 45m
    €377–899

Miami International Airport (MIA) to Florence Peretola Airport (FLR) flights

Calendar53Weekly Planes
Duration12h 57mAverage Duration
Ticket€339Cheapest Price
See schedules

Questions & Answers

Map of how to get from Port Saint Lucie to Siena.ExpandLaunch map view
  • Distance: 8,459.4 km
  • Duration: 18h 18m

What companies run services between Port Saint Lucie, FL, USA and Siena, Italy?

There is no direct connection from Port Saint Lucie to Siena. However, you can take the bus to Miami Airport, walk to Miami International Airport (MIA) airport, fly to Florence Peretola Airport (FLR), walk to Florence Airport (FLR), take the vehicle to Alamanni - Stazione Smn, walk to Firenze S.M.N., then take the train to Siena. Alternatively, you can take the bus to Orlando RedCoach Station, walk to Mccoy Rd & Central Ave, take the line 42 bus to Orlando International Airport, walk to Orlando (MCO) airport, fly to Florence Peretola Airport (FLR), walk to Florence Airport (FLR), take the vehicle to Alamanni - Stazione Smn, walk to Firenze S.M.N., then take the train to Siena.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides