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How to get fromPort Saint Lucie to South Carolinaby taxi, plane, bus, train, or car

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There are 9 ways to get from Port Saint Lucie to South Carolina by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly to Charlotte Douglas International Airport, taxi

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    3h 17m
    $272–859

  2. Drive 471 mi

    cheapest
    1. Drive from Port Saint Lucie to Charlestoncar car 471 mi
    8h 2m
    $86–125

  3. Bus, train

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus 95
    2. Take the train from West Palm Beach Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    14h 2m
    $243–469

  4. Bus, train, taxi

    1. Take the bus from Fort Pierce to Orlandobus bus
    2. Take the train from Winter Park Amtrak Station to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    5. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    16h 49m

  5. Bus to President Donald J. Trump International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at TRI RAILbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charlotte Douglas International Airport (CLT)plane plane PBI - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 49m
    $225–791

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    6h 10m
    $263–1,145

  7. Bus to Miami International Airport, fly to Charleston International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    6h 37m
    $525–1,046

  8. Bus, train via Buenaventura Lakes

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus Miami to Orlando
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    14h 10m
    $156–315

  9. Bus, train, taxi via DeLand

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Sand Lake Road to DeLandtrain train
    3. Take the train from Deland to Savannah Stationtrain train
    4. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    5. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    6. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    17h 17m

Port Saint Lucie to South Carolina by bus and train

Calendar7Weekly Services
Duration14h 10mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to South Carolina.ExpandLaunch map view
  • Distance: 578.9 mi
  • Duration: 3h 17m

What companies run services between Port Saint Lucie, FL, USA and South Carolina, USA?

There is no direct connection from Port Saint Lucie to South Carolina. However, you can take the taxi to Vero Beach Municipal Airport (VRB) airport, fly to Charlotte Douglas International Airport (CLT), then take the taxi to Rock Hill. Alternatively, you can take a vehicle from Port Saint Lucie to Charleston via GATLIN BLVD at I-95 P/R LOT, WPB ITC at TRI RAIL, West Palm Beach Amtrak Station, and Charleston Amtrak Station in around 14h 2m.

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