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How to get fromPort Saint Lucie to Tennesseeby car, plane, bus (Flixbus, Greyhound), bus, shuttle, bus (Flixbus), or bus (Greyhound)

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There are 11 ways to get from Port Saint Lucie to Tennessee by car, plane, bus (Flixbus, Greyhound), bus, shuttle, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport

    best
    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    4h 27m
    $237–1,102

  2. Bus to Fort Lauderdale–Hollywood International Airport, fly to Nashville

    cheapest
    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Nashville (BNA)plane plane FLL - BNA
    6h 36m
    $128–595

  3. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus Greyhound US0186 / ...
    15h 35m
    $161–246

  4. Drive  799.5 mi

    1. Drive from Port Saint Lucie to Nashvillecar car 799.5 mi
    13h 10m
    $137–198

  5. Bus to Orlando, fly to Mcghee Tyson Airport

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    6h 21m
    $249–1,063

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)plane plane FLL - TYS
    5h 49m
    $296–1,313

  7. Bus to Orlando, fly to Nashville

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Nashville (BNA)plane plane MCO - BNA
    7h 9m
    $196–695

  8. Bus to Orlando, fly to Memphis

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Memphis (MEM)plane plane MCO - MEM
    7h 56m
    $165–794

  9. Drive to Orlando Sanford, fly to Asheville Regional Airport, shuttle

    1. Drive from Port Saint Lucie to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Take a shuttle bus from Asheville Airport to Black Bear Resortshuttle bus
    8h 11m
    $287–602

  10. Bus via Sandy Springs

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Grand Hyatt Atlanta in Buckhead to Omni Nashville Hotelbus bus Nashville
    16h 5m
    $267–342

  11. Bus via Tallahassee

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    20h 28m
    $189–278

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar12Weekly Planes
Duration1h 38mAverage Duration
Ticket$166Cheapest Price
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Comparing Your Travel Options

Map of how to get from Port Saint Lucie to Tennessee.ExpandLaunch map view
  • Distance: 655.9 mi
  • Duration: 4h 27m

What companies run services between Port Saint Lucie, FL, USA and Tennessee, USA?

You can take a vehicle from Port Saint Lucie to Nashville Bus Station via Port St Lucie and Atlanta Bus Station in around 15h 35m.

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