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How to get fromPort Saint Lucie to Winston-Salemby taxi, plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

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There are 12 ways to get from Port Saint Lucie to Winston-Salem by taxi, plane, bus, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly to Charlotte Douglas International Airport, bus

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 56m
    $203–755

  2. Bus via Jacksonville

    cheapest
    1. Take the bus from Fort Pierce to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    21h 41m
    $103–230

  3. Bus

    1. Take the bus from Fort Pierce to Orlandobus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    17h 7m
    $120–222

  4. Bus, train via Buenaventura Lakes

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    22h
    $259–529

  5. Drive 690.2 mi

    1. Drive from Port Saint Lucie to Winston-Salemcar car 690.2 mi
    11h 32m
    $126–182

  6. Bus to Miami International Airport, fly to Piedmont Triad International Airport

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Piedmont Triad International Airport (GSO)plane plane MIA - GSO
    7h 14m
    $162–667

  7. Bus to President Donald J. Trump International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charlotte Douglas International Airport (CLT)plane plane PBI - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 27m
    $161–750

  8. Bus to Orlando, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    9h 16m
    $145–429

  9. Bus to Fort Lauderdale–Hollywood International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charlotte Douglas International Airport (CLT)plane plane FLL - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 46m
    $117–419

  10. Bus to Orlando, fly to Raleigh-Durham International Airport, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    3. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    10h
    $122–362

  11. Bus to Fort Lauderdale–Hollywood International Airport, fly to Raleigh-Durham International Airport, bus

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Raleigh-Durham International Airport (RDU)plane plane FLL - RDU
    3. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    9h 33m
    $219–922

  12. Bus, train

    1. Take the bus from Community Dr @ Robert Morgade Library to The Gardens Mallbus bus 20X
    2. Take the train from West Palm Beach Amtrak Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    25h 51m
    $268–591

Port Saint Lucie to Winston-Salem by bus

Calendar14Weekly Buses
Duration17h 7mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Port Saint Lucie to Winston-Salem.ExpandLaunch map view
  • Distance: 636 mi
  • Duration: 5h 56m

What companies run services between Port Saint Lucie, FL, USA and Winston-Salem, NC, USA?

You can take a bus from Fort Pierce to Winston Salem(Trans Center) via L B Mcleod Rd & Gardenia Ave, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, and Charlotte Bus Station in around 17h 7m.

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