Rome2Rio

How to get fromPort Saint Lucie to Wythevilleby taxi, plane, bus, bus (Flixbus), train, car, or bus (Greyhound)

Find Transport to Wytheville

See all options

There are 9 ways to get from Port Saint Lucie to Wytheville by taxi, plane, bus, bus (Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Vero Beach Municipal Airport, fly, bus

    best
    1. Take the taxi from Port Saint Lucie to Vero Beach Municipal Airport (VRB)taxi taxi
    2. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    6h 46m
    $250–800

  2. Bus via Jacksonville

    cheapest
    1. Take the bus from Fort Pierce to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Wythevillebus bus
    23h 10m
    $134–272

  3. Bus

    1. Take the bus from Fort Pierce to Orlandobus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Wythevillebus bus
    18h 36m
    $151–265

  4. Bus, train via Fayetteville

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    23h 24m
    $265–534

  5. Drive 750.7 mi

    1. Drive from Port Saint Lucie to Wythevillecar car 750.7 mi
    12h 28m
    $137–198

  6. Bus to President Donald J. Trump International Airport, fly, bus

    1. Take the bus from GATLIN BLVD at I-95 P/R LOT to WPB ITC at BAY Dbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Charlotte Douglas International Airport (CLT)plane plane PBI - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    9h 17m
    $208–795

  7. Bus to Orlando, fly, bus

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Fly from Orlando (MCO) to Charlotte Douglas International Airport (CLT)plane plane MCO - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    10h 6m
    $192–474

  8. Bus to Fort Lauderdale–Hollywood International Airport, fly, bus

    1. Take the bus from Fort Pierce to Sheridan Tri-Rail Stationbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charlotte Douglas International Airport (CLT)plane plane FLL - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    9h 36m
    $164–464

  9. Bus, train

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    24h 29m
    $288–597

Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT) flights

Calendar7Weekly Planes
Duration1h 58mAverage Duration
Ticket$109Cheapest Price
See schedules

Questions & Answers

Map of how to get from Port Saint Lucie to Wytheville.ExpandLaunch map view
  • Distance: 705.5 mi
  • Duration: 6h 46m

What companies run services between Port Saint Lucie, FL, USA and Wytheville, VA, USA?

You can take a bus from Fort Pierce to Wytheville via L B Mcleod Rd & Gardenia Ave, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Charlotte Bus Station, and Wytheville in around 18h 36m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound