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How to get fromPortland Airport (PDX) to La Crosseby plane, bus (Flixbus), train (Amtrak), car, train, or bus

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There are 9 ways to get from Portland Airport (PDX) to La Crosse by plane, bus (Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from Portland International Airport (PDX) to La Crosse (LSE)plane plane PDX - LSE
    6h 59m
    $165–605

  2. Fly to Rochester, bus

    cheapest
    1. Fly from Portland International Airport (PDX) to Rochester (RST)plane plane PDX - RST
    2. Take the bus from Rochester to La Crossebus bus
    9h 31m
    $147–578

  3. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Spokane Stationbus bus
    3. Take the bus from Spokane to Billingsbus bus
    4. Take the bus from Billings to Minneapolisbus bus
    5. Take the bus from Minneapolis to La Crossebus bus
    40h 25m
    $397–611

  4. Train (Amtrak)

    1. Take the train from Portland to La Crosse Amtrak Stationtrain train Empire Builder
    42h 35m
    $603–1,303

  5. Drive 1,825.6 mi

    1. Drive from Portland Airport (PDX) to La Crossecar car 1,825.6 mi
    28h 50m
    $334–482

  6. Fly to Minneapolis–Saint Paul International Airport, train

    1. Fly from Portland International Airport (PDX) to Minneapolis–Saint Paul International Airport (MSP)plane plane PDX - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    7h 42m
    $223–524

  7. Fly to Dane County Regional Airport-Truax Field, bus

    1. Fly from Portland International Airport (PDX) to Dane County Regional Airport-Truax Field (MSN)plane plane PDX - MSN
    2. Take the bus from Madison to La Crossebus bus
    10h 7m
    $233–864

  8. Fly to Appleton International Airport, bus

    1. Fly from Portland International Airport (PDX) to Appleton International Airport (ATW)plane plane PDX - ATW
    2. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus bus
    11h 22m
    $296–1,072

  9. Fly to Central Wisconsin Airport, bus

    1. Fly from Portland International Airport (PDX) to Central Wisconsin Airport (CWA)plane plane PDX - CWA
    2. Take the bus from Wausau Lamers to Stevens Pointbus bus
    3. Take the bus from Stevens Point Olympia Restaurant to La Crosse Grand River Stationbus bus
    10h 36m
    $176–576

Portland Airport (PDX) to La Crosse by bus

Calendar7Weekly Buses
Duration40h 25mAverage Duration
Ticket$397Cheapest Price
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Questions & Answers

Map of how to get from Portland Airport (PDX) to La Crosse.ExpandLaunch map view
  • Distance: 1,540 mi
  • Duration: 6h 59m

What companies run services between Portland Airport (PDX), USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Portland International Airport (PDX) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Portland International Airport to La Crosse via Portland Flix/Greyhound, Portland Curbside Bus Stop, Pasco Bus Stop, Spokane Station, Spokane, Billings, and Minneapolis in around 40h 25m.

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