There are 5 ways to get from Portland to Florence Station by plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Portland (PWM) to Florence Regional Airport (FLO)plane PWM - FLO
4h 42m$119–547Bus
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the bus from Boston to NYC Downtownbus
- Take the bus from New York, NY to Florence, SCbus Nyc
21h 1m$149–245Bus, train
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain
22h 20m$261–1,203Drive 932.2 mi
- Drive from Portland to Florence Stationcar 932.2 mi
16h 38m$171–246Bus via Raleigh
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the bus from South Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus
22h 38m$158–358
Portland to Florence Station by bus and train
Questions & Answers
The cheapest way to get from Portland to Florence Station is to bus which costs $140 - $250 and takes 21h 1m.
The fastest way to get from Portland to Florence Station is to fly which takes 4h 42m and costs $110 - $550.
No, there is no direct bus from Portland to Florence Station. However, there are services departing from Portland, ME and arriving at Florence, SC via Boston and New York, NY. The journey, including transfers, takes approximately 21h 1m.
The distance between Portland and Florence Station is 832 miles. The road distance is 937.6 miles.
The best way to get from Portland to Florence Station without a car is to bus which takes 21h 1m and costs $140 - $250.
It takes approximately 4h 42m to get from Portland to Florence Station, including transfers.
Portland to Florence Station bus services, operated by Concord Coach Lines, depart from Portland, ME station.
The best way to get from Portland to Florence Station is to fly which takes 4h 42m and costs $110 - $550. Alternatively, you can bus, which costs $140 - $250 and takes 21h 1m.
Portland to Florence Station bus services, operated by Concord Coach Lines, arrive at Boston, MA - South Station.
Yes, the driving distance between Portland to Florence Station is 938 miles. It takes approximately 16h 38m to drive from Portland to Florence Station.
What companies run services between Portland, ME, USA and Florence Station, SC, USA?
American Airlines flies from Portland (PWM) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a bus from Portland, ME to Florence Station via Boston, MA - South Station, Boston, NYC Downtown, New York, NY, and Florence, SC in around 21h 1m.
- Website
- aa.com
Flights from Portland to Florence Regional Airport via Charlotte
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $100–550
Flights from Portland to Florence Regional Airport via Reagan Washington, Charlotte
- Ave. Duration
- 8h 5m
- When
- Saturday
- Estimated price
- $100–550
Flights from Portland to Florence Regional Airport via Philadelphia, Charlotte
- Ave. Duration
- 8h 42m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $70–150
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Florence Station
- Ave. Duration
- 14h 41m
- Frequency
- Twice daily
- Estimated price
- $190–410
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 800 639 3317
- [email protected]
- Website
- Concord Coach Lines
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–30
- Website
- Concord Coach Lines
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–30
- Website
- Concord Coach Lines
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–30
- Website
- Concord Coach Lines
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to NYC Downtown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York, NY to Florence, SC
- Ave. Duration
- 12h
- Frequency
- 3 times a day
- Estimated price
- $85–130
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $85–130
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from South Station to Port Authority Bus Terminal
- Ave. Duration
- 4h 35m
- Frequency
- Every 2 hours
- Estimated price
- $40–110
- Website
- Peter Pan
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Raleigh Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Every 4 hours
- Estimated price
- $75–160
- Website
- Greyhound
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 45+ hotels available in Florence Station.












