There are 8 ways to get from Portland to Frederick by plane, bus, train, bus (Flixbus), car, subway, train (Amtrak), or bus (Amtrak, Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Baltimore-Washington International Airport, bus
best- Fly from Portland (PWM) to Baltimore-Washington International Airport (BWI)plane PWM - BWI
- Take the bus from Baltimore to Frederickbus
3h 50m$151–593Fly to Washington Dulles International Airport, subway, bus
cheapest- Fly from Portland (PWM) to Washington Dulles International Airport (IAD)plane PWM - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
5h 20m$92–509Bus, train
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus Bwi
12h 13mBus via New York
- Take the bus from City of Portland to New York Midtownbus
- Take the bus from New York Midtown to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore to Frederickbus
13h 26m$154–249Drive 539.2 mi
- Drive from Portland to Frederickcar 539.2 mi
9h 59m$99–143Fly to Ronald Reagan Washington National Airport, bus
- Fly from Portland (PWM) to Ronald Reagan Washington National Airport (DCA)plane PWM - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
4h 34m$119–667Train
- Take the train from Portland to Bostontrain
- Take the train from Boston to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
13h 13m$319–502Bus
- Take the bus from Portland, ME to Boston, MA - South Stationbus
- Take the bus from Boston to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore to Frederickbus
13h 30m$156–273
Portland to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Portland to Frederick is to drive which costs $95 - $150 and takes 9h 59m.
The fastest way to get from Portland to Frederick is to fly and bus which takes 3h 50m and costs $150 - $600.
No, there is no direct bus from Portland to Frederick. However, there are services departing from City of Portland and arriving at Frederick via New York Midtown and Baltimore. The journey, including transfers, takes approximately 13h 26m.
No, there is no direct train from Portland to Frederick. However, there are services departing from Portland and arriving at FREDERICK MARC wb via North Station, Boston and Washington Union Station. The journey, including transfers, takes approximately 13h 13m.
The distance between Portland and Frederick is 505 miles. The road distance is 542.3 miles.
The best way to get from Portland to Frederick without a car is to bus and train which takes 12h 13m and costs .
It takes approximately 3h 50m to get from Portland to Frederick, including transfers.
Portland to Frederick bus services, operated by Flixbus USA, depart from City of Portland station.
Portland to Frederick train services, operated by Amtrak, depart from Portland station.
The best way to get from Portland to Frederick is to bus via New York which takes 13h 26m and costs $150 - $250. Alternatively, you can train, which costs $310 - $500 and takes 13h 13m.
What companies run services between Portland, ME, USA and Frederick, MD, USA?
You can take a bus from City of Portland to Frederick via New York Midtown and Baltimore in around 13h 26m. Alternatively, you can take a train from Portland to FREDERICK MARC wb via Boston, North Station, Back Bay, Boston, and Washington Union Station in around 13h 13m.
- Website
- southwest.com
Flights from Portland to Baltimore-Washington International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $80–490
- Website
- aa.com
Flights from Portland to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $110–700
Flights from Portland to Ronald Reagan Washington National Airport via Philadelphia
- Ave. Duration
- 4h 6m
- When
- Wednesday and Saturday
- Estimated price
- $110–700
Flights from Portland to Ronald Reagan Washington National Airport via New York La Guardia
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–700
- Website
- united.com
Flights from Portland to Ronald Reagan Washington National Airport via Newark
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $110–700
Flights from Portland to Washington Dulles International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $85–500
- Website
- delta.com
Flights from Portland to Ronald Reagan Washington National Airport via New York La Guardia
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $110–700
Flights from Portland to Ronald Reagan Washington National Airport via New York JFK
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- $100–170
- Website
- Amtrak
Train from Portland to Boston
- Ave. Duration
- 2h 32m
- Frequency
- Every 4 hours
- Estimated price
- $60–100
- Website
- Amtrak
Train from Boston to Washington Union Station
- Ave. Duration
- 8h 10m
- Frequency
- Every 4 hours
- Estimated price
- $250–390
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 2h 32m
- Frequency
- 5 times a day
- Estimated price
- $45–700
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $45–480
- First Class
- $180–700
Train from Boston to Washington Union Station
- Ave. Duration
- 6h 56m
- Frequency
- Every 4 hours
- Estimated price
- $100–900
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $100–550
- First Class
- $310–900
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 50 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from Washington Union Station to FREDERICK MARC wb
- Ave. Duration
- 1h 41m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $65–110
- Schedules at
- BayRunner Shuttle
Bus from Baltimore to Frederick
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $65–110
- Schedules at
- BayRunner Shuttle
- Phone
- +1 800 639 3317
- [email protected]
- Website
- Concord Coach Lines
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Bus from Portland, ME to Boston, MA - South Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from BWI Amtrak Station to Frederick Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from City of Portland to New York Midtown
- Ave. Duration
- 7h 16m
- Frequency
- 6 times a week
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
Bus from New York Midtown to Baltimore Downtown Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Boston to Baltimore Downtown Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- Twice daily
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Baltimore Downtown Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Once daily
- Estimated price
- $80–120
- Website
- Greyhound
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Booking & Getting There
Portland to Frederick bus services, operated by Flixbus USA, arrive at New York Midtown station.
Portland to Frederick train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Portland to Frederick is 542 miles. It takes approximately 9h 59m to drive from Portland to Frederick.
Book your Portland to Frederick train tickets online with Omio.
Book your Portland to Frederick bus tickets online with Omio.
There are 55+ hotels available in Frederick.




















