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How to get fromPortland to Greenvilleby plane, bus (Amtrak, Flixbus), bus, train, car, taxi, or bus (Amtrak, Greyhound)

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There are 6 ways to get from Portland to Greenville by plane, bus (Amtrak, Flixbus), bus, train, car, taxi, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from Portland (PWM) to Greenville–Spartanburg International Airport (GSP)plane plane PWM - GSP
    4h 28m
    $191–814

  2. Drive 1,009 mi

    cheapest
    1. Drive from Portland to Greenvillecar car 1,009 mi
    18h 31m
    $185–266

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Gastonia, NC - Chester St.bus bus Nyc
    4. Take the bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenvillebus bus
    20h 48m
    $196–387

  4. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    24h 14m
    $307–1,345

  5. Fly to Asheville Regional Airport, taxi

    1. Fly from Portland (PWM) to Asheville Regional Airport (AVL)plane plane PWM - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 33m
    $245–693

  6. Bus via Atlanta

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from South Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    32h 22m
    $254–585

Portland (PWM) to Greenville–Spartanburg International Airport (GSP) flights

Calendar85Weekly Planes
Duration5h 30mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Portland to Greenville.ExpandLaunch map view
  • Distance: 889 mi
  • Duration: 4h 28m

What companies run services between Portland, ME, USA and Greenville, SC, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Portland (PWM) to Greenville–Spartanburg International Airport (GSP) every 2 hours. Alternatively, you can take a bus from Portland, ME to Greenville via Boston, MA - South Station, Boston, NYC Downtown, New York, NY, Gastonia, NC - Chester St., Los Arcos Restaurant - Gastonia, and Taqueria Guadalajara - Greenville in around 20h 48m.

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