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How to get fromPortland to Hyannisby bus (Amtrak), train, bus, car, plane, or bus (Flixbus, Greyhound)

Find Transport to Hyannis

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There are 8 ways to get from Portland to Hyannis by bus (Amtrak), train, bus, car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    4h 27m
    $48–78
  2. Drive  175.5 mi

    cheapest
    1. Drive from Portland to Hyanniscar car 175.5 mi
    3h 21m
    $30–44
  3. Train, bus

    1. Take the train from Portland to Bostontrain train Downeaster
    2. Take the bus from Boston to Hyannisbus bus Bz 0956 / ...
    5h 32m
    $80–125
  4. Fly from Portland

    1. Fly from Portland (PWM) to Barnstable Municipal Airport (HYA)plane plane PWM - HYA
    5h 15m
    $100–600
  5. Bus via City of Portland

    1. Take the bus from City of Portland to Bostonbus bus FlixBus N2615
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    4h 28m
    $44–64
  6. Bus via Boston

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the bus from Boston to Hyannisbus bus Bz 0956 / ...
    4h 39m
    $35–68
  7. Bus #2

    1. Take the bus from Portland, ME to Logan International Airportbus bus Portland / ...
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    4h 54m
    $52–71
  8. Bus to Boston Logan Airport, fly

    1. Take the bus from Portland, ME to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA)plane plane BOS - HYA
    3h 46m
    $144–341

Portland to Hyannis by bus

Calendar119Weekly Buses
Duration4h 27mAverage Duration
Ticket$48Cheapest Price
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Comparing Your Travel Options

What companies run services between Portland, ME, USA and Hyannis, MA, USA?

You can take a bus from Portland, ME to Hyannis Transportation Center via Boston, MA - South Station and Boston South Buses in around 4h 27m. Alternatively, American Airlines, JetBlue Airways, and two other airlines fly from Portland (PWM) to Barnstable Municipal Airport (HYA) 3 times a day.

Airlines
Bus operators

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