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How to get fromPortland to Indianaby plane, train, bus (Amtrak, Flixbus), bus, car, bus (Amtrak, Greyhound), or train (Amtrak)

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There are 8 ways to get from Portland to Indiana by plane, train, bus (Amtrak, Flixbus), bus, car, bus (Amtrak, Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Chicago O'Hare International Airport, train

    best
    1. Fly from Portland (PWM) to Chicago O'Hare International Airport (ORD)plane plane PWM - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 55m
    $91–421

  2. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Indianapolisbus bus
    24h 27m
    $171–283

  3. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolisbus bus
    25h 23m
    $472–808

  4. Drive  1,007.8 mi

    1. Drive from Portland to Indianapoliscar car 1,007.8 mi
    18h 7m
    $184–266

  5. Fly Portland to South Bend, train

    1. Fly from Portland (PWM) to South Bend (SBN)plane plane PWM - SBN
    2. Take the train from South Bend Airport to Gary Metro Centertrain train
    7h 8m
    $111–523

  6. Bus to Boston Logan Airport, fly to Indianapolis

    1. Take the bus from Portland, ME to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Indianapolis (IND)plane plane BOS - IND
    6h 47m
    $226–983

  7. Bus via Indianapolis Union Station

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    25h 47m
    $196–313

  8. Train (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    31h 39m
    $617–1,651

Portland to Indiana by bus

Calendar9Weekly Buses
Duration24h 27mAverage Duration
Ticket$171Cheapest Price
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Comparing Your Travel Options

Map of how to get from Portland to Indiana.ExpandLaunch map view
  • Distance: 945.4 mi
  • Duration: 4h 55m

What companies run services between Portland, ME, USA and Indiana, USA?

You can take a bus from Portland, ME to Indianapolis via Boston, MA - South Station, Boston, and New York Midtown in around 24h 27m. Alternatively, you can take a train from Portland to Indianapolis via Boston, North Station, Back Bay, Boston, and Ny Moynihan Train Hall At Penn Station in around 31h 39m.

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