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How to get fromPortland to Lafayetteby plane, bus (Amtrak, Greyhound, Flixbus), bus, train, car, shuttle, or train (Amtrak)

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There are 9 ways to get from Portland to Lafayette by plane, bus (Amtrak, Greyhound, Flixbus), bus, train, car, shuttle, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Purdue University Airport

    best
    1. Fly from Portland (PWM) to Purdue University Airport (LAF)plane plane PWM - LAF
    7h 21m
    $119–563

  2. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lafayette Amtrak Stationbus bus
    28h
    $180–383

  3. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    29h 18m
    $366–823

  4. Drive 1,010.1 mi

    1. Drive from Portland to Lafayettecar car 1,010.1 mi
    19h 16m
    $185–267

  5. Fly to Indianapolis, shuttle

    1. Fly from Portland (PWM) to Indianapolis (IND)plane plane PWM - IND
    2. Take a shuttle bus from Indianapolis Airport to Holiday Inn City Centreshuttle bus
    5h 56m
    $164–773

  6. Fly to Chicago Midway International Airport, train

    1. Fly from Portland (PWM) to Chicago Midway International Airport (MDW)plane plane PWM - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 27m
    $145–604

  7. Fly to Chicago O'Hare International Airport, train

    1. Fly from Portland (PWM) to Chicago O'Hare International Airport (ORD)plane plane PWM - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 56m
    $126–523

  8. Bus, train via New York

    1. Take the bus from City of Portland to New York Midtownbus bus FlixBus N2615
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Lafayette Amtrak Stationtrain train Cardinal
    33h 37m
    $362–784

  9. Train (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Lafayette Amtrak Stationtrain train
    33h 44m
    $399–1,528

Portland to Lafayette by bus

Calendar9Weekly Buses
Duration28hAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Portland to Lafayette.ExpandLaunch map view
  • Distance: 883 mi
  • Duration: 7h 21m

What companies run services between Portland, ME, USA and Lafayette, IN, USA?

United Airlines, American Airlines, and Delta fly from Portland (PWM) to Purdue University Airport (LAF) 5 times a day. Alternatively, you can take a bus from Portland, ME to Lafayette Amtrak Station via Boston, MA - South Station, Boston, Newark Penn Station, and Indianapolis Union Station in around 28h.

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