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How to get fromPortland to Mechanicsburgby plane, bus (Amtrak, Greyhound), train (Amtrak), car, train, bus, or bus (Flixbus)

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There are 7 ways to get from Portland to Mechanicsburg by plane, bus (Amtrak, Greyhound), train (Amtrak), car, train, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Portland to Harrisburg International Airport

    best
    1. Fly from Portland (PWM) to Harrisburg International Airport (MDT)plane plane PWM - MDT
    5h 32m
    $73–411

  2. Bus via Boston

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from South Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Harrisburg Bus Stationbus bus
    13h 9m
    $92–230

  3. Train (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Newark Penn Stationtrain train
    3. Take the train from Newark Penn Station to Harrisburgtrain train
    13h 14m
    $151–951

  4. Drive 479.7 mi

    1. Drive from Portland to Mechanicsburgcar car 479.7 mi
    9h 7m
    $88–127

  5. Fly Portland to Philadelphia International Airport, train

    1. Fly from Portland (PWM) to Philadelphia International Airport (PHL)plane plane PWM - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    6h 15m
    $122–602

  6. Bus to Boston Logan Airport, fly to Harrisburg International Airport

    1. Take the bus from Portland, ME to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Harrisburg International Airport (MDT)plane plane BOS - MDT
    6h 26m
    $75–353

  7. Bus (Flixbus)

    1. Take the bus from City of Portland to New York Midtownbus bus FlixBus N2615
    2. Take the bus from New York Midtown to Harrisburg Bus Stationbus bus FlixBus N2640 / ...
    13h 10m
    $85–150

Portland to Mechanicsburg by bus and foot

Calendar66Weekly Services
Duration13h 9mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Portland to Mechanicsburg.ExpandLaunch map view
  • Distance: 427.1 mi
  • Duration: 5h 32m

What companies run services between Portland, ME, USA and Mechanicsburg, Cumberland County, PA, USA?

United Airlines, American Airlines, and Delta fly from Portland (PWM) to Harrisburg International Airport (MDT) every 3 hours. Alternatively, you can take a bus from Portland, ME to E Main St & Arch St WB via Boston, MA - South Station, South Station, Port Authority Bus Terminal, Harrisburg Bus Station, and Market Square Transfer Center in around 13h 9m.

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