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How to get fromPortland to Natickby bus, train, train (Amtrak), or car

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There are 4 ways to get from Portland to Natick by bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the train from South Station to Natick Centertrain train Framingham/Worcester Line
    3h 19m
    $24–52

  2. Bus, train via City of Portland

    cheapest
    1. Take the bus from City of Portland to Bostonbus bus FlixBus N2615
    2. Take the train from South Station to Natick Centertrain train Framingham/Worcester Line
    3h 20m
    $20–37

  3. Train (Amtrak)

    1. Take the train from Portland to Bostontrain train Downeaster
    4h
    $69–109

  4. Drive  120.4 mi

    1. Drive from Portland to Natickcar car 120.4 mi
    2h 23m
    $22–32

Portland to Natick by bus and train

Calendar125Weekly Services
Duration3h 19mAverage Duration
Ticket$24Cheapest Price
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Comparing Your Travel Options

Map of how to get from Portland to Natick.ExpandLaunch map view
  • Distance: 122.9 mi
  • Duration: 3h 19m

What companies run services between Portland, ME, USA and Natick, MA, USA?

Amtrak operates a train from Portland to Boston every 4 hours. Tickets cost $60–100 and the journey takes 2h 32m.

Train operators
Bus operators

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