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How to get fromPortland to Sanibel Islandby plane, train, bus, bus (Amtrak, Flixbus, Greyhound), or car

Find Transport to Sanibel Island

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There are 5 ways to get from Portland to Sanibel Island by plane, train, bus, bus (Amtrak, Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Portland (PWM) to Ft. Myers (RSW)plane plane PWM - RSW
    4h 26m
    $239–817
  2. Train, bus (Amtrak)

    1. Take the train from Portland to Bostontrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Orlandotrain train
    4. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus
    38h 17m
    $579–1,778
  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    38h 23m
    $302–516
  4. Drive 1,546.7 mi

    1. Drive from Portland to Sanibel Islandcar car 1,546.7 mi
    27h 24m
    $283–408
  5. Bus, train

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus
    2. Take the bus from South Station to Port Authority Bus Terminalbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Orlandotrain train
    4. Take the bus from Orlando to Fort Myers Amtrak Bus Stopbus bus
    38h 35m
    $551–1,113

Portland (PWM) to Ft. Myers (RSW) flights

Calendar32Weekly Planes
Duration5h 34mAverage Duration
Ticket$163Cheapest Price
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Questions & Answers

What companies run services between Portland, ME, USA and Sanibel Island, FL, USA?

Breeze Airways, Southwest Airlines, and two other airlines fly from Portland (PWM) to Ft. Myers (RSW) 5 times a day. Alternatively, you can take a bus from Portland, ME to Sanibel Island via Boston, MA - South Station, Boston, Baltimore Downtown Bus Station, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 38h 23m.

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