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How to get fromPortland to Florenceby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 5 ways to get from Portland to Florence by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Portland International Airport (PDX) to Florence Regional Airport (FLO)plane plane PDX - FLO
    10h 59m
    $183–716

  2. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 17h
    $473–903

  3. Train, bus

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    3d 3h
    $1,116–2,208

  4. Drive 2,834 mi

    1. Drive from Portland to Florencecar car 2,834 mi
    46h 24m
    $518–748

  5. Fly to Fayetteville Municipal Airport, train

    1. Fly from Portland International Airport (PDX) to Fayetteville Municipal Airport (FAY)plane plane PDX - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    11h 57m
    $226–777

Portland to Florence by bus

Calendar7Weekly Buses
Duration2d 17hAverage Duration
Ticket$473Cheapest Price
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Questions & Answers

Map of how to get from Portland to Florence.ExpandLaunch map view
  • Distance: 2,385.7 mi
  • Duration: 10h 59m

What companies run services between Portland, OR, USA and Florence, SC, USA?

American Airlines, Southwest Airlines, and Alaska Airlines, Inc. fly from Portland International Airport (PDX) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a bus from Portland Curbside Bus Stop to Florence Bus Station via Pasco Bus Stop, Denver Union Station, St Louis Bus Station, and Atlanta Bus Station in around 2d 17h.

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