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How to get fromPortland to Florenceby plane, bus (Flixbus, Greyhound), train, bus, car, or train (Amtrak)

Find Transport to Florence

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There are 7 ways to get from Portland to Florence by plane, bus (Flixbus, Greyhound), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Portland International Airport (PDX) to Florence Regional Airport (FLO)plane plane PDX - FLO
    10h 16m
    $143–616

  2. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 17h
    $466–772

  3. Train, bus

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Florence Bus Stationbus bus
    2d 22h
    $648–1,519

  4. Drive  2,834 mi

    1. Drive from Portland to Florencecar car 2,834 mi
    46h 24m
    $518–748

  5. Fly to Myrtle Beach, bus

    1. Fly from Portland International Airport (PDX) to Myrtle Beach (MYR)plane plane PDX - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    11h 32m
    $144–584

  6. Fly to Fayetteville Municipal Airport, train

    1. Fly from Portland International Airport (PDX) to Fayetteville Municipal Airport (FAY)plane plane PDX - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    12h 3m
    $169–672

  7. Train (Amtrak)

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    3d 4h
    $851–2,054

Portland to Florence by bus

Calendar7Weekly Buses
Duration2d 17hAverage Duration
Ticket$466Cheapest Price
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Comparing Your Travel Options

Map of how to get from Portland to Florence.ExpandLaunch map view
  • Distance: 2,385.7 mi
  • Duration: 10h 16m

What companies run services between Portland, OR, USA and Florence, SC, USA?

American Airlines flies from Portland International Airport (PDX) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Portland Curbside Bus Stop to Florence Bus Station via Pasco Bus Stop, Denver Union Station, St Louis Bus Station, and Atlanta Bus Station in around 2d 17h.

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Want to know more about travelling around United States

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Related travel guides

Need to know: Greyhound

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