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How to get fromPortland to Florenceby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Florence

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There are 6 ways to get from Portland to Florence by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Portland International Airport (PDX) to Florence Regional Airport (FLO)plane plane PDX - FLO
    10h 46m
    $143–616

  2. Bus

    1. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    2. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 15h
    $519–820

  3. Train, bus

    1. Take the train from Portland to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    3d 3h
    $1,816–2,894

  4. Drive  2,834 mi

    1. Drive from Portland to Florencecar car 2,834 mi
    46h 24m
    $518–748

  5. Fly to Myrtle Beach, bus

    1. Fly from Portland International Airport (PDX) to Myrtle Beach (MYR)plane plane PDX - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    11h 7m
    $146–585

  6. Fly to Fayetteville Municipal Airport, train

    1. Fly from Portland International Airport (PDX) to Fayetteville Municipal Airport (FAY)plane plane PDX - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    11h 21m
    $194–692

Portland to Florence by bus

Calendar7Weekly Buses
Duration2d 15hAverage Duration
Ticket$519Cheapest Price
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Comparing Your Travel Options

Map of how to get from Portland to Florence.ExpandLaunch map view
  • Distance: 2,385.7 mi
  • Duration: 10h 46m

What companies run services between Portland, OR, USA and Florence, SC, USA?

American Airlines, Alaska Airlines, Inc., and two other airlines fly from Portland International Airport (PDX) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a bus from Portland Curbside Bus Stop to Florence Bus Station via Pasco Bus Stop, Denver Union Station, St Louis Bus Station, and Atlanta Bus Station in around 2d 15h.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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