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How to get fromPortland to La Mesaby plane, tram, bus (Greyhound), train (Amtrak), or car

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There are 4 ways to get from Portland to La Mesa by plane, tram, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, tram

    best
    1. Fly from Portland International Airport (PDX) to San Diego International Airport (SAN)plane plane PDX - SAN
    2. Take the tram from Civic Center Station to La Mesa Blvd Stationtram tram
    5h 22m
    $87–323

  2. Bus (Greyhound)

    1. Take the bus from Portland Curbside Bus Stop to Sacramento Bus Stationbus bus Greyhound US0500
    2. Take the bus from Sacramento Bus Station to San Diego Greyhound Bus Stopbus bus Greyhound US0831
    30h 4m
    $180–338

  3. Train (Amtrak)

    1. Take the train from Portland to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    35h 2m
    $436–875

  4. Drive 1,085.6 mi

    1. Drive from Portland to La Mesacar car 1,085.6 mi
    18h 20m
    $199–287

Portland to La Mesa by bus (Greyhound)

Calendar7Weekly Buses
Duration30h 4mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Portland to La Mesa.ExpandLaunch map view
  • Distance: 961.9 mi
  • Duration: 5h 22m

What companies run services between Portland, OR, USA and La Mesa, CA, USA?

You can take a bus from Portland Curbside Bus Stop to University Av & Allison Av via Sacramento Bus Station, San Diego Greyhound Bus Stop, Old Town Transit Center, and University Av & College Av in around 30h 4m. Alternatively, you can take a train from Portland to 70th Street Station via Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 35h 2m.

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