There are 5 ways to get from Portland to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Portland International Airport
best- Fly from Portland International Airport (PDX) to Lambert–St. Louis International Airport (STL)plane PDX - STL
7h 28m$186–456Bus
- Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus
- Take the bus from Pasco Bus Stop to Denver Union Stationbus
- Take the bus from Denver Union Station to St Louis Bus Stationbus
45h 10m$342–557Train (Amtrak)
- Take the train from Portland to Chicago Union Stationtrain Empire Builder
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
2d 3h$614–1,436Drive 2,025.8 mi
- Drive from Portland to St. Louiscar 2,025.8 mi
32h 12m$370–534Train to Seattle-Tacoma International Airport, fly
- Take the train from Portland to Tacomatrain
- Fly from Seattle-Tacoma International Airport (SEA) to Lambert–St. Louis International Airport (STL)plane SEA - STL
9h 9m$232–478
Portland to St. Louis by bus
Comparing Your Travel Options
The cheapest way to get from Portland to St. Louis is to fly which costs $180 - $460 and takes 7h 28m.
The fastest way to get from Portland to St. Louis is to fly which takes 7h 28m and costs $180 - $460.
No, there is no direct bus from Portland to St. Louis station. However, there are services departing from Portland Curbside Bus Stop and arriving at St Louis Bus Station via Pasco Bus Stop and Denver Union Station. The journey, including transfers, takes approximately 45h 10m.
No, there is no direct train from Portland to St. Louis. However, there are services departing from Portland and arriving at St. Louis via Chicago Union Station. The journey, including transfers, takes approximately 2 days 3h.
The distance between Portland and St. Louis is 1739 miles. The road distance is 2037.6 miles.
The best way to get from Portland to St. Louis without a car is to bus which takes 45h 10m and costs $340 - $600.
It takes approximately 7h 28m to get from Portland to St. Louis, including transfers.
Portland to St. Louis bus services, operated by Flixbus USA, depart from Portland Curbside Bus Stop station.
Portland to St. Louis train services, operated by Amtrak, depart from Portland station.
The best way to get from Portland to St. Louis is to fly which takes 7h 28m and costs $180 - $460. Alternatively, you can bus, which costs $340 - $600 and takes 45h 10m, you could also train, which costs $600 - $1,500 and takes 2 days 3h.
What companies run services between Portland, OR, USA and St. Louis, MO, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Portland International Airport (PDX) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Portland Curbside Bus Stop to St Louis Bus Station via Pasco Bus Stop and Denver Union Station in around 45h 10m.
- Website
- southwest.com
Flights from Portland International Airport to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $140–650
Flights from Portland International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $160–700
Flights from Portland International Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 7h
- When
- Sunday
- Estimated price
- $170–750
Flights from Seattle-Tacoma International Airport to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $140–650
Flights from Seattle-Tacoma International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 6h 10m
- When
- Sunday
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Portland to Chicago Union Station
- Ave. Duration
- 46h
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $65–160
- Website
- Amtrak
Train from Portland to Tacoma
- Ave. Duration
- 2h 33m
- Frequency
- Every 4 hours
- Estimated price
- $30–80
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portland Curbside Bus Stop to Pasco Bus Stop
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Portland to St. Louis bus services, operated by Flixbus USA, arrive at Pasco Bus Stop station.
St. Louis is 2h ahead of Portland. It is currently 4:00 PM in Portland and 6:00 PM in St. Louis.
Portland to St. Louis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Portland to St. Louis is 2038 miles. It takes approximately 32h 12m to drive from Portland to St. Louis.
Book your Portland to St. Louis train tickets online with Omio.
Book your Portland to St. Louis bus tickets online with Omio and FlixBus.
There are 559+ hotels available in St. Louis.