There are 3 ways to get from Portsmouth to Brookline by bus (Flixbus, Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Portsmouth Bus Stop to Bostonbus FlixBus N2615
- Take the bus from Essex St @ Atlantic Ave to Nubianbus Sl4
1h 37m$10–21Drive 58.6 mi
- Drive from Portsmouth to Brooklinecar 58.6 mi
1h 15m$11–16Bus via Terminal A - Arrivals, LEX Pick Up
- Take the bus from Portsmouth to Bostonbus Cj00:40-Lgpm
2h 38m$25–41
Portsmouth to Brookline by bus
Questions & Answers
The cheapest way to get from Portsmouth to Brookline is to drive which costs $10 - $16 and takes 1h 15m.
The fastest way to get from Portsmouth to Brookline is to drive which takes 1h 15m and costs $10 - $16.
No, there is no direct bus from Portsmouth to Brookline. However, there are services departing from Portsmouth Bus Stop and arriving at Nubian via Essex St @ Atlantic Ave. The journey, including transfers, takes approximately 1h 37m.
The distance between Portsmouth and Brookline is 61 miles. The road distance is 59 miles.
The best way to get from Portsmouth to Brookline without a car is to bus which takes 1h 37m and costs $9 - $22.
It takes approximately 1h 37m to get from Portsmouth to Brookline, including transfers.
Portsmouth to Brookline bus services, operated by Flixbus USA, depart from Portsmouth Bus Stop station.
Portsmouth to Brookline bus services, operated by Flixbus USA, arrive at Boston station.
Yes, the driving distance between Portsmouth to Brookline is 59 miles. It takes approximately 1h 15m to drive from Portsmouth to Brookline.
There are 1426+ hotels available in Brookline.
What companies run services between Portsmouth, NH, USA and Brookline, MA, USA?
You can take a bus from Portsmouth Bus Stop to Nubian via Boston and Essex St @ Atlantic Ave in around 1h 37m.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Essex St @ Atlantic Ave to Nubian
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $1–5
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
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