Rome2Rio

How to get fromPortsmouth to Gainesvilleby bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Find Transport to Gainesville

See all options

There are 10 ways to get from Portsmouth to Gainesville by bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Portland, fly to Gainesville Regional Airport

    best
    1. Take the bus from Portsmouth Bus Stop to City of Portlandbus bus
    2. Fly from Portland (PWM) to Gainesville Regional Airport (GNV)plane plane PWM - GNV
    9h 25m
    $141–670

  2. Bus to Boston Logan Airport, fly to Jacksonville, bus

    cheapest
    1. Take the bus from Portsmouth to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Jacksonville (JAX)plane plane BOS - JAX
    3. Take the bus from Jacksonville to Gainesvillebus bus
    9h 38m
    $126–597

  3. Bus, train

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Jacksonvilletrain train
    4. Take the bus from Jacksonville to Gainesvillebus bus
    29h 7m
    $370–1,436

  4. Bus

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York City Chinatown to Jacksonvillebus bus
    4. Take the bus from Jacksonville to Gainesvillebus bus
    29h 38m
    $199–338

  5. Drive 1,251.6 mi

    1. Drive from Portsmouth to Gainesvillecar car 1,251.6 mi
    21h 59m
    $229–330

  6. Bus to Boston Logan Airport, fly to Orlando, bus

    1. Take the bus from Portsmouth to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Orlando (MCO)plane plane BOS - MCO
    3. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    9h 33m
    $196–784

  7. Bus, bus to Manchester Airport, fly to Gainesville Regional Airport

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Gainesville Regional Airport (GNV)plane plane MHT - GNV
    11h 59m
    $138–633

  8. Bus to Boston Logan Airport, fly to Tampa, bus

    1. Take the bus from Portsmouth to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Tampa (TPA)plane plane BOS - TPA
    3. Take the bus from Tampa Bus Station to Gainesvillebus bus
    10h 41m
    $157–964

  9. Bus, bus to Manchester Airport, fly to Orlando

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Orlando (MCO)plane plane MHT - MCO
    4. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    11h 2m
    $247–688

  10. Bus via Atlanta

    1. Take the bus from Portsmouth to Bostonbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    37h 10m
    $228–452

Portsmouth to Gainesville by bus and train

Calendar4Weekly Services
Duration29h 7mAverage Duration
Ticket$370Cheapest Price
See schedules

Questions & Answers

Map of how to get from Portsmouth to Gainesville.ExpandLaunch map view
  • Distance: 1,231.5 mi
  • Duration: 9h 25m

What companies run services between Portsmouth, NH, USA and Gainesville, FL, USA?

You can take a bus from Portsmouth Bus Stop to Gainesville via Boston, NYC Downtown, New York City Chinatown, and Jacksonville in around 29h 38m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers