There are 5 ways to get from Portsmouth to Hopkinton by bus, train, train (Amtrak), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Portsmouth Bus Stop to Bostonbus FlixBus N2615
- Take the train from South Station to Framinghamtrain Framingham/Worcester Line
3h 52m$15–28Bus
cheapest- Take the bus from Portsmouth Bus Stop to Bostonbus FlixBus N2615
- Take the bus from Boston to Framinghambus Greyhound US0270s
4h 12m$14–25Train
- Take the train from Dover to Bostontrain Downeaster
- Take the train from Back Bay to Southboroughtrain Framingham/Worcester Line
6h 3m$32–62Drive 86.1 mi
- Drive from Portsmouth to Hopkintoncar 86.1 mi
1h 32m$16–23Bus, train via Boston Airport (BOS)
- Take the bus from Portsmouth to Bostonbus Cj00:40-Lgpm
- Take the train from Back Bay to Framinghamtrain Framingham/Worcester Line
4h 50m$29–48
Portsmouth to Hopkinton by bus and train
Questions & Answers
The cheapest way to get from Portsmouth to Hopkinton is to bus which costs $13 - $26 and takes 4h 12m.
The fastest way to get from Portsmouth to Hopkinton is to drive which takes 1h 32m and costs $15 - $23.
No, there is no direct bus from Portsmouth to Hopkinton. However, there are services departing from Portsmouth Bus Stop and arriving at Hopkinton Center via Boston and Framingham MBTA Station. The journey, including transfers, takes approximately 4h 12m.
No, there is no direct train from Portsmouth to Hopkinton. However, there are services departing from Dover and arriving at Southborough via North Station and Back Bay. The journey, including transfers, takes approximately 6h 3m.
The distance between Portsmouth and Hopkinton is 87 miles. The road distance is 86.6 miles.
The best way to get from Portsmouth to Hopkinton without a car is to bus and train which takes 3h 52m and costs $14 - $29.
It takes approximately 3h 52m to get from Portsmouth to Hopkinton, including transfers.
Portsmouth to Hopkinton bus services, operated by Flixbus USA, depart from Portsmouth Bus Stop station.
Portsmouth to Hopkinton train services, operated by Amtrak, depart from Dover station.
The best way to get from Portsmouth to Hopkinton is to train which takes 6h 3m and costs $30 - $65. Alternatively, you can bus, which costs $13 - $26 and takes 4h 12m.
What companies run services between Portsmouth, NH, USA and Hopkinton, MA, USA?
You can take a bus from Hanover Station to Hopkinton Center via Dover Transportation Center, Dover, Boston, North Station, Back Bay, Back Bay, Southborough, and Southborough MBTA Station in around 6h 3m. Alternatively, you can take a bus from Portsmouth Bus Stop to Hopkinton Center via Boston, Framingham, and Framingham MBTA Station in around 4h 12m.
Train from South Station to Framingham
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $4–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–10
Train from Back Bay to Southborough
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Back Bay to Framingham
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Dover to Boston
- Ave. Duration
- 1h 33m
- Frequency
- Every 4 hours
- Estimated price
- $21–45
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston to Framingham
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $3–7
- Website
- Greyhound
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Want to know more about travelling around United States
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More Questions & Answers
Portsmouth to Hopkinton bus services, operated by Flixbus USA, arrive at Boston station.
Portsmouth to Hopkinton train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Portsmouth to Hopkinton is 87 miles. It takes approximately 1h 32m to drive from Portsmouth to Hopkinton.
There are 120+ hotels available in Hopkinton.


















