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How to get fromPortsmouth to Indianapolisby bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

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There are 8 ways to get from Portsmouth to Indianapolis by bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly

    best
    1. Take the bus from Portsmouth to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Indianapolis (IND)plane plane BOS - IND
    6h 28m
    $197–979

  2. Bus, bus to Manchester Airport, fly

    cheapest
    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Indianapolis (IND)plane plane MHT - IND
    9h 26m
    $158–783

  3. Bus (Flixbus)

    1. Take the bus from Portsmouth Bus Stop to New York Midtownbus bus FlixBus N2615
    2. Take the bus from New York Midtown to Indianapolisbus bus FlixBus N2642 / ...
    23h 35m
    $164–271

  4. Bus, train via Toledo

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolis, INbus bus
    24h 33m
    $270–631

  5. Drive 958.3 mi

    1. Drive from Portsmouth to Indianapoliscar car 958.3 mi
    17h 20m
    $175–253

  6. Bus to Portland, fly

    1. Take the bus from Portsmouth Bus Stop to City of Portlandbus bus
    2. Fly from Portland (PWM) to Indianapolis (IND)plane plane PWM - IND
    8h 7m
    $161–770

  7. Bus via Boston

    1. Take the bus from Portsmouth to Bostonbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    26h 32m
    $166–325

  8. Bus, train

    1. Take the bus from Portsmouth Bus Stop to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    30h 4m
    $349–1,416

Portsmouth to Indianapolis by bus (Flixbus)

Calendar8Weekly Buses
Duration23h 35mAverage Duration
Ticket$164Cheapest Price
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Questions & Answers

Map of how to get from Portsmouth to Indianapolis.ExpandLaunch map view
  • Distance: 887.8 mi
  • Duration: 6h 28m

What companies run services between Portsmouth, NH, USA and Indianapolis, IN, USA?

You can take a bus from Portsmouth Bus Stop to Indianapolis via New York Midtown in around 23h 35m.

Airlines
Train operators
Bus operators

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