There are 8 ways to get from Portsmouth to Myrtle Beach by bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Boston Logan Airport, fly to Myrtle Beach
best- Take the bus from Portsmouth to Bostonbus
- Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane BOS - MYR
5h 8m$91–401Bus
- Take the bus from Portsmouth Bus Stop to Bostonbus
- Take the bus from Boston to NYC Downtownbus
- Take the bus from New York, NY to Camdenbus Nyc
- Take the bus from Camden to Myrtle Beach Bus Stationbus
26h 4m$146–236Bus, train
- Take the bus from Portsmouth Bus Stop to Bostonbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
27h 26m$284–1,236Drive 899.9 mi
- Drive from Portsmouth to Myrtle Beachcar 899.9 mi
16h 48m$165–238Bus, bus to Manchester Airport, fly to Myrtle Beach
- Take the bus from Portsmouth Bus Stop to Bostonbus
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Myrtle Beach (MYR)plane MHT - MYR
6h 41m$107–475Bus, train to Theodore Francis Green State Airport, fly to Myrtle Beach
- Take the bus from Portsmouth Bus Stop to Bostonbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Myrtle Beach (MYR)plane PVD - MYR
6h 59m$179–386Bus to Boston Logan Airport, fly to Wilmington International Airport, bus
- Take the bus from Portsmouth to Bostonbus
- Fly from Boston Logan Airport (BOS) to Wilmington International Airport (ILM)plane BOS - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
7h 39m$115–487Bus via Raleigh
- Take the bus from Portsmouth to Bostonbus
- Take the bus from Boston to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus
30h 22m$191–385
Portsmouth to Myrtle Beach by bus and train
Questions & Answers
The cheapest way to get from Portsmouth to Myrtle Beach is to bus which costs $140 - $240 and takes 26h 4m.
The fastest way to get from Portsmouth to Myrtle Beach is to bus and fly which takes 5h 8m and costs $90 - $410.
No, there is no direct bus from Portsmouth to Myrtle Beach station. However, there are services departing from Portsmouth Bus Stop and arriving at Myrtle Beach Bus Station via Boston, New York, NY and Camden. The journey, including transfers, takes approximately 26h 4m.
The distance between Portsmouth and Myrtle Beach is 802 miles. The road distance is 905.1 miles.
The best way to get from Portsmouth to Myrtle Beach without a car is to bus which takes 26h 4m and costs $140 - $240.
It takes approximately 5h 8m to get from Portsmouth to Myrtle Beach, including transfers.
Portsmouth to Myrtle Beach bus services, operated by Flixbus USA, depart from Portsmouth Bus Stop station.
Portsmouth to Myrtle Beach bus services, operated by Flixbus USA, arrive at Boston station.
Yes, the driving distance between Portsmouth to Myrtle Beach is 905 miles. It takes approximately 16h 48m to drive from Portsmouth to Myrtle Beach.
Book your Portsmouth to Myrtle Beach bus tickets online with Omio.
What companies run services between Portsmouth, NH, USA and Myrtle Beach, SC, USA?
You can take a bus from Portsmouth Bus Stop to Myrtle Beach Bus Station via Boston, NYC Downtown, New York, NY, and Camden in around 26h 4m.
- Website
- aa.com
Flights from Boston Logan Airport to Myrtle Beach
- Ave. Duration
- 2h 25m
- When
- Friday and Saturday
- Estimated price
- $65–360
Flights from Manchester Airport to Myrtle Beach via Philadelphia
- Ave. Duration
- 4h 32m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–430
Flights from Manchester Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $90–450
Flights from Manchester Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–430
Flights from Theodore Francis Green State Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $65–350
Flights from Theodore Francis Green State Airport to Myrtle Beach via Reagan Washington
- Ave. Duration
- 4h 29m
- When
- Monday to Saturday
- Estimated price
- $60–330
Flights from Theodore Francis Green State Airport to Myrtle Beach via Philadelphia
- Ave. Duration
- 4h 34m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–330
Flights from Boston Logan Airport to Wilmington International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $75–420
Flights from Boston Logan Airport to Wilmington International Airport via Philadelphia
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $80–430
Flights from Boston Logan Airport to Wilmington International Airport via Reagan Washington
- Ave. Duration
- 4h 32m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $80–430
Flights from Boston Logan Airport to Wilmington International Airport via New York La Guardia
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–430
- Website
- southwest.com
Flights from Boston Logan Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $65–360
Flights from Manchester Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 5m
- When
- Saturday to Friday
- Estimated price
- $80–430
Flights from Theodore Francis Green State Airport to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $60–330
- Website
- delta.com
Flights from Boston Logan Airport to Myrtle Beach
- Ave. Duration
- 2h 17m
- When
- Saturday and Sunday
- Estimated price
- $65–360
Flights from Boston Logan Airport to Wilmington International Airport
- Ave. Duration
- 2h 12m
- When
- Saturday
- Estimated price
- $75–420
Flights from Boston Logan Airport to Wilmington International Airport via New York La Guardia
- Ave. Duration
- 4h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–430
- Website
- united.com
Flights from Boston Logan Airport to Wilmington International Airport via Newark
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $80–430
- Website
- flybreeze.com
Flights from Manchester Airport to Myrtle Beach
- Ave. Duration
- 2h 25m
- When
- Monday and Friday
- Estimated price
- $160–950
Flights from Theodore Francis Green State Airport to Myrtle Beach
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $150–340
- Website
- jetblue.com
Flights from Boston Logan Airport to Wilmington International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $75–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $70–160
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Station
- Ave. Duration
- 10h 47m
- Frequency
- Twice daily
- Estimated price
- $170–360
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Boston to NYC Downtown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Boston to Port Authority Bus Terminal
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Raleigh Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Every 4 hours
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Raleigh Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- Greyhound
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York, NY to Camden
- Ave. Duration
- 13h 39m
- Frequency
- Once daily
- Estimated price
- $90–130
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $90–130
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