There are 3 ways to get from Portsmouth to Natick by bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Portsmouth Bus Stop to Bostonbus FlixBus N2615
- Take the train from South Station to Natick Centertrain Framingham/Worcester Line
2h 37m$12–25Drive 70.9 mi
- Drive from Portsmouth to Natickcar 70.9 mi
1h 34m$13–19Bus, train via Terminal A - Arrivals, LEX Pick Up
- Take the bus from Portsmouth to Bostonbus Cj00:40-Lgpm
- Take the train from Back Bay to Natick Centertrain Framingham/Worcester Line
3h 35m$27–45
Portsmouth to Natick by bus and train
Questions & Answers
The cheapest way to get from Portsmouth to Natick is to drive which costs $12 - $19 and takes 1h 34m.
The fastest way to get from Portsmouth to Natick is to drive which takes 1h 34m and costs $12 - $19.
The distance between Portsmouth and Natick is 76 miles. The road distance is 71.3 miles.
The best way to get from Portsmouth to Natick without a car is to bus and train which takes 2h 37m and costs $11 - $26.
It takes approximately 2h 37m to get from Portsmouth to Natick, including transfers.
Yes, the driving distance between Portsmouth to Natick is 71 miles. It takes approximately 1h 34m to drive from Portsmouth to Natick.
There are 468+ hotels available in Natick.
What companies run services between Portsmouth, NH, USA and Natick, MA, USA?
There is no direct connection from Portsmouth to Natick. However, you can take the bus to Boston, walk to South Station, then take the train to Natick Center. Alternatively, you can drive from Portsmouth to Natick in around 1h 34m.
Train from South Station to Natick Center
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Back Bay to Natick Center
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Portsmouth Bus Stop to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Portsmouth to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
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