There are 7 ways to get from Potosí to Santiago by bus, plane, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Alcantari Airport, fly
best- Take the bus from Potosi to Sucrebus
- Fly from Alcantari Airport (SRE) to Comodoro Arturo Merino Benítez International Airport (SCL)plane SRE - SCL
10h 55m$413–719Bus
cheapest- Take the bus from Potosí to Orurobus La Paz-Tarija
- Take the bus from Oruro to Terminal Alameda - Turbusbus Santa Cruz
40h 2m$63–77Bus via Calama
- Take the bus from Potosí to Uyunibus
- Take the bus from Uyuni to Terminal de Buses Calamabus
- Take the bus from Terminal de Buses Calama to Terminal San Borjabus
32h 44m$120–170Drive 2,124.2 km
- Drive from Potosí to Santiagocar 2,124.2 km
26h 46m$262–379Bus to Cochabamba, fly
- Take the bus from Potosí to Cochabambabus
- Fly from Cochabamba (CBB) to Comodoro Arturo Merino Benítez International Airport (SCL)plane CBB - SCL
11h 18mBus to Tarija, fly
- Take the bus from Potosí to Tarijabus
- Fly from Tarija (TJA) to Comodoro Arturo Merino Benítez International Airport (SCL)plane TJA - SCL
16h 21m$364–678Bus, bus to Calama Airport, fly
- Take the bus from Potosí to Uyunibus
- Take the bus from Uyuni to Terminal de Buses Calamabus
- Fly from Calama Airport (CJC) to Comodoro Arturo Merino Benítez International Airport (SCL)plane CJC - SCL
15h 18m$118–282
Alcantari Airport (SRE) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Questions & Answers
The cheapest way to get from Potosí to Santiago is to bus which costs $60 - $80 and takes 40h 2m.
The fastest way to get from Potosí to Santiago is to bus and fly which takes 10h 55m and costs $410 - $750.
No, there is no direct bus from Potosí to Santiago. However, there are services departing from Potosí and arriving at Terminal San Borja via Uyuni and Terminal de Buses Calama. The journey, including transfers, takes approximately 32h 44m.
The distance between Potosí and Santiago is 1865 km. The road distance is 2124.2 km.
The best way to get from Potosí to Santiago without a car is to bus via Calama which takes 32h 44m and costs $120 - $170.
It takes approximately 10h 55m to get from Potosí to Santiago, including transfers.
Potosí to Santiago bus services, operated by Expreso 11 de Julio, depart from Potosí station.
Potosí to Santiago bus services, operated by Expreso 11 de Julio, arrive at Uyuni station.
Yes, the driving distance between Potosí to Santiago is 2124 km. It takes approximately 26h 46m to drive from Potosí to Santiago.
There are 3441+ hotels available in Santiago.
What companies run services between Potosí, Bolivia and Santiago, Chile?
You can take a bus from Potosí to Terminal San Borja via Uyuni and Terminal de Buses Calama in around 32h 44m.
- Website
- latam.com
Flights from Alcantari Airport to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 5h 24m
- When
- Thursday and Saturday
- Estimated price
- $190–700
Flights from Cochabamba to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 5h 4m
- When
- Wednesday and Saturday
- Estimated price
- $170–600
Flights from Tarija to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 14h 40m
- When
- Tuesday
- Estimated price
- $180–650
Flights from Tarija to Comodoro Arturo Merino Benítez International Airport via Santa Cruz, Iquique
- Ave. Duration
- 10h 9m
- When
- Wednesday and Saturday
- Estimated price
- $200–700
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $60–170
- Website
- skyairline.com
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $24–170
- Website
- jetsmart.com
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $30–140
- Website
- boa.bo
Flights from Alcantari Airport to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 8h 10m
- When
- Tuesday and Friday
- Estimated price
- $400–650
Flights from Cochabamba to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 5h 5m
- When
- Tuesday and Friday
- Estimated price
- $220–480
Flights from Tarija to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 12h 40m
- When
- Tuesday and Friday
- Estimated price
- $250–700
Flights from Tarija to Comodoro Arturo Merino Benítez International Airport via Cochabamba, Santa Cruz
- Ave. Duration
- 14h
- When
- Tuesday and Friday
- Estimated price
- $250–700
- Phone
- +591 71160539
- Website
- Real Audiencia
Bus from Potosi to Sucre
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $3
- Schedules at
- Real Audiencia
- Phone
- +591 684 06 744
- Website
- Trans Alonso de Ibañez
Bus from Potosi to Sucre
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- Trans Alonso de Ibañez
- Phone
- +591 72323251
- Website
- facebook.com
Bus from Potosí to Uyuni
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $14–21
- Book at
- busbud.com
Bus from Potosí to Uyuni
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $14–21
- Book at
- busbud.com
- Phone
- +56 9 8149 3691
- [email protected]
Bus from Uyuni to Terminal de Buses Calama
- Ave. Duration
- 5h 29m
- Frequency
- 4 times a week
- Estimated price
- $55–80
- Book at
- ticketsbolivia.com
- Road
- $55–80
Bus from Uyuni to Terminal de Buses Calama
- Ave. Duration
- 5h 29m
- Frequency
- 4 times a week
- Estimated price
- $55–80
- Book at
- ticketsbolivia.com
- Road
- $55–80
- [email protected]
- Website
- ciktur.cl
Bus from Terminal de Buses Calama to Terminal San Borja
- Ave. Duration
- 21h 15m
- Frequency
- Every 4 hours
- Estimated price
- $52–70
- Schedules at
- kupos.cl
- Cama
- $60–70
- Semi Cama
- $55–70
- Phone
- +591 60340030
- [email protected]
- Website
- Trans Imperial Potosí
Bus from Potosí to Cochabamba
- Ave. Duration
- 4h
- Frequency
- Once daily
- Schedules at
- Trans Imperial Potosí
Bus from Potosí to Tarija
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $15
- Website
- Linea Sindical Flota Villa Imperial
- Phone
- +591 466-60443
- [email protected]
- Website
- Autotransportes SAMA
Bus from Potosí to Oruro
- Ave. Duration
- 5h 53m
- Frequency
- Once daily
- Estimated price
- $18–35
- Schedules at
- Autotransportes SAMA
- Phone
- +591 2527 7355
- [email protected]
- Website
- Jet Nort Super Class
Bus from Oruro to Terminal Alameda - Turbus
- Ave. Duration
- 33h 3m
- Frequency
- 4 times a week
- Estimated price
- $44
- Schedules at
- Jet Nort Super Class
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