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How to get fromPoughkeepsie to Durhamby train, plane, bus (Flixbus), train (Amtrak), car, or bus

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There are 10 ways to get from Poughkeepsie to Durham by train, plane, bus (Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Raleigh-Durham International Airport

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane plane LGA - RDU
    6h 28m
    $102–502

  2. Drive 553 mi

    cheapest
    1. Drive from Poughkeepsie to Durhamcar car 553 mi
    10h 5m
    $101–146

  3. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to 9th Ave & W 30th Stbus bus ShortLine Hudson
    2. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    15h 17m
    $109–193

  4. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    15h 21m
    $204–417

  5. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    6h 19m
    $290–1,281

  6. Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane plane JFK - RDU
    6h 45m
    $489–1,753

  7. Train to Laguardia Airport, fly to Piedmont Triad International Airport, train

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane plane LGA - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 21m
    $177–811

  8. Train to Westchester County Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane plane HPN - RDU
    8h 17m
    $125–601

  9. Train to Stewart International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    1. Take the train from Poughkeepsie to Beacontrain train
    2. Fly from Stewart International Airport (SWF) to Raleigh-Durham International Airport (RDU)plane plane SWF - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    6h 4m
    $165–1,125

  10. Train, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train Hudson
    2. Take the bus from Port Authority Bus Terminal to Durhambus bus Greyhound US0670
    16h 7m
    $107–197

Poughkeepsie to Durham by train and bus

Calendar5Weekly Services
Duration15h 17mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Durham.ExpandLaunch map view
  • Distance: 523.3 mi
  • Duration: 6h 28m

What companies run services between Poughkeepsie, NY, USA and Durham, NC, USA?

You can take a train from Poughkeepsie to Durham via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, 9th Ave & W 30th St, and New York Midtown in around 15h 17m. Alternatively, you can take a train from Poughkeepsie Amtrak Station to Durham Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 15h 21m.

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