Rome2Rio

How to get fromPoughkeepsie to Florenceby train, plane, bus, train (Amtrak), or car

Find Transport to Florence

See all options

There are 10 ways to get from Poughkeepsie to Florence by train, plane, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Myrtle Beach, bus

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Myrtle Beach (MYR)plane plane LGA - MYR
    3. Take the bus from Myrtle Beach to Florencebus bus
    7h 59m
    $141–494

  2. Bus

    cheapest
    1. Take the bus from Newburgh ShortLine Transportation Center to Broadway & Murray Stbus bus ShortLine Hudson
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    17h 42m
    $113–191

  3. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    17h 11m
    $224–467

  4. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from New York City Chinatown to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Florence Bus Stationbus bus
    17h 36m
    $129–222

  5. Drive 694.9 mi

    1. Drive from Poughkeepsie to Florencecar car 694.9 mi
    12h 28m
    $127–184

  6. Train to Newark Liberty International Airport, fly to Myrtle Beach, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Myrtle Beach (MYR)plane plane EWR - MYR
    3. Take the bus from Myrtle Beach to Florencebus bus
    7h 59m
    $454–893

  7. Fly Stewart International Airport to Myrtle Beach, bus

    1. Fly from Stewart International Airport (SWF) to Myrtle Beach (MYR)plane plane SWF - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    7h 47m
    $399–837

  8. Train to Westchester County Airport, fly to Myrtle Beach, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Myrtle Beach (MYR)plane plane HPN - MYR
    3. Take the bus from Myrtle Beach to Florencebus bus
    9h 49m
    $259–1,213

  9. Train to Laguardia Airport, fly to Raleigh-Durham International Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane plane LGA - RDU
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    10h 46m
    $219–526

  10. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    10h 37m
    $312–1,325

Poughkeepsie to Florence by train (Amtrak)

Calendar14Weekly Trains
Duration17h 11mAverage Duration
Ticket$224Cheapest Price
See schedules

Questions & Answers

Map of how to get from Poughkeepsie to Florence.ExpandLaunch map view
  • Distance: 717.6 mi
  • Duration: 7h 59m

What companies run services between Poughkeepsie, NY, USA and Florence, SC, USA?

You can take a train from Poughkeepsie Amtrak Station to Florence Station via Ny Moynihan Train Hall At Penn Station in around 17h 11m. Alternatively, you can take a train from Poughkeepsie to Florence, SC via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Broadway & Murray St, Broadway/Warren St, Madison St/Pike St, and New York, NY in around 17h 42m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers