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How to get fromPoughkeepsie to Florenceby train, plane, bus, train (Amtrak), or car

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There are 8 ways to get from Poughkeepsie to Florence by train, plane, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly, bus

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Myrtle Beach (MYR)plane plane LGA - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    7h 58m
    $117–517

  2. Fly from Stewart International Airport, bus

    cheapest
    1. Fly from Stewart International Airport (SWF) to Myrtle Beach (MYR)plane plane SWF - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    7h 44m
    $90–400

  3. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    17h 11m
    $179–446

  4. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Broadway & Chambers Stbus bus ShortLine Hudson
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    17h 42m
    $113–191

  5. Drive  694.9 mi

    1. Drive from Poughkeepsie to Florencecar car 694.9 mi
    12h 28m
    $127–184

  6. Train to Newark Liberty International Airport, fly, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Myrtle Beach (MYR)plane plane EWR - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    7h 57m
    $411–705

  7. Train to Westchester County Airport, fly, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Myrtle Beach (MYR)plane plane HPN - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    9h 54m
    $160–726

  8. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from New York City Chinatown to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Florence Bus Stationbus bus
    17h 50m
    $125–198

Poughkeepsie to Florence by train (Amtrak)

Calendar14Weekly Trains
Duration17h 11mAverage Duration
Ticket$179Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Florence.ExpandLaunch map view
  • Distance: 709.6 mi
  • Duration: 7h 58m

What companies run services between Poughkeepsie, NY, USA and Florence, SC, USA?

You can take a train from Poughkeepsie Amtrak Station to Florence Station via Ny Moynihan Train Hall At Penn Station in around 17h 11m. Alternatively, you can take a train from Poughkeepsie to Florence, SC via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Broadway & Chambers St, Broadway/Warren St, Madison St/Pike St, and New York, NY in around 17h 42m.

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