Rome2Rio

How to get fromPoughkeepsie to Indianapolisby train, plane, bus, car, bus (Flixbus), or train (Amtrak)

Find Transport to Indianapolis

See all options

There are 9 ways to get from Poughkeepsie to Indianapolis by train, plane, bus, car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Indianapolis (IND)plane plane LGA - IND
    6h 30m
    $223–588

  2. Train, bus

    cheapest
    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train Hudson
    2. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    20h 12m
    $132–257

  3. Train, bus via Toledo

    1. Take the train from Poughkeepsie Amtrak Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    18h 8m
    $196–448

  4. Drive 753.2 mi

    1. Drive from Poughkeepsie to Indianapoliscar car 753.2 mi
    12h 53m
    $138–199

  5. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Indianapolis (IND)plane plane EWR - IND
    6h 28m
    $212–1,173

  6. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Indianapolis (IND)plane plane JFK - IND
    7h 1m
    $435–1,649

  7. Train, train to Philadelphia International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Indianapolis (IND)plane plane PHL - IND
    7h 55m
    $154–1,448

  8. Bus

    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus ShortLine Hudson
    2. Take the bus from New York Midtown to Indianapolisbus bus FlixBus N2642 / ...
    21h 19m
    $132–226

  9. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train Cardinal
    25h 45m
    $269–643

Poughkeepsie to Indianapolis by train and bus

Calendar7Weekly Services
Duration18h 8mAverage Duration
Ticket$196Cheapest Price
See schedules

Questions & Answers

Map of how to get from Poughkeepsie to Indianapolis.ExpandLaunch map view
  • Distance: 749.6 mi
  • Duration: 6h 30m

What companies run services between Poughkeepsie, NY, USA and Indianapolis, IN, USA?

You can take a train from Poughkeepsie to Indianapolis via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, and New York Midtown in around 21h 19m. Alternatively, you can take a train from Poughkeepsie Amtrak Station to Indianapolis via Ny Moynihan Train Hall At Penn Station in around 25h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers