Rome2Rio

How to get fromPoughkeepsie to Key Westby train, plane, bus, car, or bus (Flixbus, Greyhound)

Find Transport to Key West

See all options

There are 8 ways to get from Poughkeepsie to Key West by train, plane, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Key West International Airport (EYW)plane plane EWR - EYW
    6h 45m
    $158–533

  2. Train to Laguardia Airport, fly

    cheapest
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Key West International Airport (EYW)plane plane LGA - EYW
    7h 2m
    $142–599

  3. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from Newark Penn Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    36h 1m
    $259–384

  4. Train, bus via Pembroke Pines

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    38h 25m
    $817–1,306

  5. Drive  1,503.5 mi

    1. Drive from Poughkeepsie to Key Westcar car 1,503.5 mi
    26h 26m
    $275–397

  6. Train, train to Philadelphia International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane plane PHL - EYW
    8h 7m
    $183–1,228

  7. Train to Westchester County Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Key West International Airport (EYW)plane plane HPN - EYW
    10h 57m
    $200–858

  8. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from White Plains Bus Station to Richmondbus bus
    3. Take the bus from Richmond to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    39h 27m
    $240–387

Poughkeepsie to Key West by train, subway, foot, and bus

Calendar4Weekly Services
Duration36h 1mAverage Duration
Ticket$259Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Poughkeepsie to Key West.ExpandLaunch map view
  • Distance: 1,286.5 mi
  • Duration: 6h 45m

What companies run services between Poughkeepsie, NY, USA and Key West, FL, USA?

You can take a bus from Metro North Station to N Roosevelt & 3rd Street via TransCenter, White Plains Bus Station, Richmond, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 39h 27m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound