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How to get fromPoughkeepsie to Lewistonby train, bus, bus (Greyhound, Flixbus), car, or plane

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There are 11 ways to get from Poughkeepsie to Lewiston by train, bus, bus (Greyhound, Flixbus), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via New York

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the bus from Boston to Lewiston Bus Stopbus bus
    10h 23m
    $186–302

  2. Drive  307.6 mi

    cheapest
    1. Drive from Poughkeepsie to Lewistoncar car 307.6 mi
    6h 1m
    $55–79

  3. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from White Plains Bus Station to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    4. Take the bus from Boston to Lewiston Bus Stopbus bus
    12h 21m
    $60–102

  4. Train to Laguardia Airport, fly to Portland, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Portland (PWM)plane plane LGA - PWM
    3. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    7h 26m
    $89–470

  5. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Albany-Rensselaer Amtrak Stationtrain train
    2. Take the train from Albany-Rensselaer Amtrak Station to Bostontrain train
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    4. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    11h 41m
    $157–384

  6. Train, bus #2

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train
    3. Take the bus from Boston to Lewiston Bus Stopbus bus
    11h 51m
    $171–270

  7. Train, bus #3

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Take the bus from New York Midtown to City of Portlandbus bus
    3. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    12h 29m
    $78–127

  8. Train to Newark Liberty International Airport, fly to Portland, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Portland (PWM)plane plane EWR - PWM
    3. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    7h 23m
    $120–445

  9. Train to John F. Kennedy International Airport, fly to Portland, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Portland (PWM)plane plane JFK - PWM
    3. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    7h 47m
    $81–331

  10. Train to Laguardia Airport, fly to Bangor, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Bangor (BGR)plane plane LGA - BGR
    3. Take the bus from Bangor Park & Ride to Lewiston Bus Stopbus bus
    8h 37m
    $119–526

  11. Train to Laguardia Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    3. Take the bus from Logan International Airport to Portland, MEbus bus
    4. Take the bus from City of Portland to Lewiston Bus Stopbus bus
    9h 29m
    $112–525

Poughkeepsie to Lewiston by train and bus

Calendar7Weekly Services
Duration10h 23mAverage Duration
Ticket$186Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Lewiston.ExpandLaunch map view
  • Distance: 448.8 mi
  • Duration: 10h 23m

What companies run services between Poughkeepsie, NY, USA and Lewiston, ME, USA?

You can take a bus from Metro North Station to Lewiston Bus Stop via TransCenter, White Plains Bus Station, Hartford Union Station, and Boston in around 12h 21m.

Airlines
Train operators
Bus operators

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