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How to get fromPoughkeepsie to Louisvilleby train, plane, bus, car, or bus (Greyhound)

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There are 10 ways to get from Poughkeepsie to Louisville by train, plane, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Louisville International Airport

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    6h 49m
    $142–689

  2. Bus

    cheapest
    1. Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus
    24h 8m
    $137–313

  3. Train, bus via Toledo

    1. Take the train from Poughkeepsie Amtrak Station to Toledotrain train
    2. Take the bus from Toledo to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    21h 33m
    $258–534

  4. Train, bus

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Take the bus from New York Midtown to Cincinnatibus bus
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    22h 40m
    $142–275

  5. Drive 774.5 mi

    1. Drive from Poughkeepsie to Louisvillecar car 774.5 mi
    13h 49m
    $142–205

  6. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    6h 40m
    $140–578

  7. Train to Laguardia Airport, fly to Blue Grass Airport, drive

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 42m
    $204–1,005

  8. Train to Laguardia Airport, fly to Covington, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Covington (CVG)plane plane LGA - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    9h 15m
    $152–783

  9. Train to Newark Liberty International Airport, fly to Covington, bus

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Covington (CVG)plane plane EWR - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    9h 6m
    $315–1,222

  10. Train, bus #2 (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    29h 10m
    $356–742

Poughkeepsie to Louisville by train and bus

Calendar7Weekly Services
Duration21h 33mAverage Duration
Ticket$258Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Louisville.ExpandLaunch map view
  • Distance: 739.3 mi
  • Duration: 6h 49m

What companies run services between Poughkeepsie, NY, USA and Louisville, KY, USA?

You can take a train from Poughkeepsie to Louisville, KY Bus Station via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, and N Wilson Rd & Ferrell Pl - Columbus in around 24h 8m.

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