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How to get fromPoughkeepsie to Portland, MEby train, bus, car, plane, train (Amtrak), or bus (Greyhound, Flixbus, Amtrak)

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There are 11 ways to get from Poughkeepsie to Portland, ME by train, bus, car, plane, train (Amtrak), or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Boston

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the train from 125th Street - Harlem to Stamfordtrain train
    3. Take the train from Stamford Amtrak Station to Bostontrain train
    4. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    8h 19m
    $99–210

  2. Bus

    cheapest
    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from Stamford Bus Stop to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    4. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    10h 39m
    $47–105

  3. Train, bus

    1. Take the train from Poughkeepsie to New York Penn Stationtrain train VIA Rail
    2. Take the bus from New York Midtown to City of Portlandbus bus FlixBus N2615
    10h 7m
    $65–232

  4. Drive 276.2 mi

    1. Drive from Poughkeepsie to Portland, MEcar car 276.2 mi
    5h 28m
    $51–73

  5. Train to Laguardia Airport, fly to Portland

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Portland (PWM)plane plane LGA - PWM
    5h 16m
    $86–486

  6. Train

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the train from 125th Street - Harlem to Stamfordtrain train
    3. Take the train from Stamford Amtrak Station to Bostontrain train
    4. Take the train from Boston to Portlandtrain train
    9h 36m
    $111–238

  7. Train, bus via Pittsfield

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    9h 41m
    $93–204

  8. Train to Newark Liberty International Airport, fly to Portland

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Portland (PWM)plane plane EWR - PWM
    5h 16m
    $480–2,071

  9. Train to John F. Kennedy International Airport, fly to Portland

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Portland (PWM)plane plane JFK - PWM
    5h 44m
    $83–397

  10. Train to Laguardia Airport, fly to Boston Logan Airport, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    3. Take the bus from Logan International Airport to Portland, MEbus bus
    7h 14m
    $93–436

  11. Train, train to Philadelphia International Airport, fly to Portland

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Portland (PWM)plane plane PHL - PWM
    6h 59m
    $122–1,146

Poughkeepsie to Portland, ME by train and bus

Calendar114Weekly Services
Duration8h 19mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Poughkeepsie to Portland, ME.ExpandLaunch map view
  • Distance: 398.1 mi
  • Duration: 8h 19m

What companies run services between Poughkeepsie, NY, USA and Portland, ME, USA?

You can take a train from Poughkeepsie to Portland via 125th Street - Harlem, Stamford, Stamford Amtrak Station, Boston, Back Bay, North Station, and Boston in around 9h 36m. Alternatively, you can take a bus from Metro North Station to Portland, ME via White Plains Transportation Center, Stamford Transportation Center @ Bay A, Stamford Bus Stop, Hartford Union Station, Boston, and Boston, MA - South Station in around 10h 39m.

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