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How to get fromPoughkeepsie to San Diegoby train, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or bus

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There are 8 ways to get from Poughkeepsie to San Diego by train, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to San Diego International Airport (SAN)plane plane EWR - SAN
    8h 59m
    $250–969

  2. Train, train to Philadelphia International Airport, fly

    cheapest
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to San Diego International Airport (SAN)plane plane PHL - SAN
    10h 27m
    $181–1,105

  3. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 17h
    $804–1,862

  4. Bus

    1. Take the bus from Metro North Station to TransCenterbus bus
    2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    3d 2h
    $484–794

  5. Drive  2,792.3 mi

    1. Drive from Poughkeepsie to San Diegocar car 2,792.3 mi
    46h
    $510–737

  6. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to San Diego International Airport (SAN)plane plane JFK - SAN
    9h 25m
    $223–1,147

  7. Train to Westchester County Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to San Diego International Airport (SAN)plane plane HPN - SAN
    12h 47m
    $329–1,345

  8. Train, bus

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Take the bus from New York City Chinatown to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d
    $737–1,616

Poughkeepsie to San Diego by train (Amtrak)

Calendar7Weekly Trains
Duration2d 17hAverage Duration
Ticket$804Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to San Diego.ExpandLaunch map view
  • Distance: 2,507 mi
  • Duration: 8h 59m

What companies run services between Poughkeepsie, NY, USA and San Diego, CA, USA?

You can take a train from Poughkeepsie Amtrak Station to San Diego via Chicago Union Station and Fullerton Amtrak Station in around 2d 17h. Alternatively, you can take a bus from Metro North Station to San Diego via TransCenter, White Plains Station, New York Midtown, Port Authority Bus Terminal, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 3d 2h.

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