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How to get fromPoughkeepsie to South Carolinaby train, plane, train (Amtrak), car, or taxi

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There are 8 ways to get from Poughkeepsie to South Carolina by train, plane, train (Amtrak), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Greenville–Spartanburg International Airport

    best
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Greenville–Spartanburg International Airport (GSP)plane plane LGA - GSP
    5h 48m
    $196–881

  2. Train to Laguardia Airport, fly to Columbia

    cheapest
    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Columbia (CAE)plane plane LGA - CAE
    6h 51m
    $113–538

  3. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    17h 1m
    $460–751

  4. Drive  795.9 mi

    1. Drive from Poughkeepsie to Charlestoncar car 795.9 mi
    15h 2m
    $136–197

  5. Train to Laguardia Airport, fly to Charleston International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Charleston International Airport (CHS)plane plane LGA - CHS
    6h 28m
    $123–638

  6. Train to Newark Liberty International Airport, fly to Charleston International Airport

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Charleston International Airport (CHS)plane plane EWR - CHS
    6h 25m
    $514–892

  7. Train to Westchester County Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Charlotte Douglas International Airport (CLT)plane plane HPN - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    7h 48m
    $319–1,345

  8. Train to Westchester County Airport, fly to Charleston International Airport

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Westchester County Airport (HPN) to Charleston International Airport (CHS)plane plane HPN - CHS
    8h 23m
    $201–997

Laguardia Airport (LGA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar93Weekly Planes
Duration3h 23mAverage Duration
Ticket$143Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to South Carolina.ExpandLaunch map view
  • Distance: 698.1 mi
  • Duration: 5h 48m

What companies run services between Poughkeepsie, NY, USA and South Carolina, USA?

You can take a train from Poughkeepsie Amtrak Station to Charleston via Ny Moynihan Train Hall At Penn Station and Charleston Amtrak Station in around 17h 1m.

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