There are 8 ways to get from Poughkeepsie to Spartanburg by train, plane, train (Amtrak), bus (Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Laguardia Airport, fly to Greenville–Spartanburg International Airport
best- Take the train from Poughkeepsie to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Greenville–Spartanburg International Airport (GSP)plane LGA - GSP
5h 39m$206–856Train to Laguardia Airport, fly to Asheville Regional Airport, drive
cheapest- Take the train from Poughkeepsie to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Asheville Regional Airport (AVL)plane LGA - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
6h 19m$115–541Train (Amtrak)
- Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Spartanburg Stationtrain Crescent
16h 51m$189–432Bus
- Take the bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminalbus ShortLine Hudson
- Take the bus from New York Midtown to Spartanburgbus FlixBus N2471
19h 49m$145–242Drive 724.4 mi
- Drive from Poughkeepsie to Spartanburgcar 724.4 mi
14h 4m$133–191Train to Newark Liberty International Airport, fly to Greenville–Spartanburg International Airport
- Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Greenville–Spartanburg International Airport (GSP)plane EWR - GSP
5h 46m$195–740Train to Newark Liberty International Airport, fly to Asheville Regional Airport, drive
- Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane EWR - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
6h 8m$119–475Train, bus
- Take the train from Poughkeepsie to Grand Central Terminaltrain Hudson
- Take the bus from Port Authority Bus Terminal to Spartanburgbus Greyhound US0670
22h 3m$155–253
Poughkeepsie to Spartanburg by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Poughkeepsie to Spartanburg is to drive which costs $130 - $200 and takes 14h 4m.
The fastest way to get from Poughkeepsie to Spartanburg is to train and fly which takes 5h 39m and costs $200 - $900.
No, there is no direct bus from Poughkeepsie station to Spartanburg. However, there are services departing from Beacon Station and arriving at Spartanburg via Newburgh ShortLine Transportation Center and New York Midtown. The journey, including transfers, takes approximately 19h 49m.
No, there is no direct train from Poughkeepsie station to Spartanburg station. However, there are services departing from Poughkeepsie Amtrak Station and arriving at Spartanburg Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 16h 51m.
The distance between Poughkeepsie and Spartanburg is 709 miles. The road distance is 728.6 miles.
The best way to get from Poughkeepsie to Spartanburg without a car is to train which takes 16h 51m and costs $180 - $440.
It takes approximately 5h 39m to get from Poughkeepsie to Spartanburg, including transfers.
Poughkeepsie to Spartanburg bus services, operated by Rockland Coaches, depart from Newburgh ShortLine Transportation Center station.
Poughkeepsie to Spartanburg train services, operated by Amtrak, depart from Poughkeepsie Amtrak Station.
The best way to get from Poughkeepsie to Spartanburg is to train which takes 16h 51m and costs $180 - $440. Alternatively, you can bus, which costs $140 - $250 and takes 19h 49m.
What companies run services between Poughkeepsie, NY, USA and Spartanburg, SC, USA?
You can take a train from Poughkeepsie Amtrak Station to Spartanburg Station via Ny Moynihan Train Hall At Penn Station in around 16h 51m. Alternatively, you can take a train from Poughkeepsie to Spartanburg via Beacon, Beacon Station, Newburgh ShortLine Transportation Center, Port Authority Bus Terminal, New York Midtown, and Spartanburg in around 19h 49m.
- Website
- aa.com
Flights from Laguardia Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $130–750
Flights from Laguardia Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $130–750
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $110–650
Flights from Laguardia Airport to Asheville Regional Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $85–490
Flights from Laguardia Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $90–500
Flights from Laguardia Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $85–490
Flights from Newark Liberty International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $70–400
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from Poughkeepsie to 125th Street - Harlem
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $18–28
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $18–21
- Peak
- $25–28
Train from Poughkeepsie to 125th Street - Harlem
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $18–28
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $18–21
- Peak
- $25–28
Train from Poughkeepsie to Grand Central Terminal
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- $19–29
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $19–22
- Peak
- $26–29
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from Newburgh ShortLine Transportation Center to Port Authority Bus Terminal
- Ave. Duration
- 1h 36m
- Frequency
- Every 4 hours
- Estimated price
- $13–28
- Schedules at
- Rockland Coaches
- Adult
- $13–28
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Booking & Getting There
Poughkeepsie to Spartanburg bus services, operated by Rockland Coaches, arrive at Port Authority Bus Terminal station.
Poughkeepsie to Spartanburg train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Poughkeepsie to Spartanburg is 729 miles. It takes approximately 14h 4m to drive from Poughkeepsie to Spartanburg.
Book your Poughkeepsie to Spartanburg train tickets online with Omio.
There are 83+ hotels available in Spartanburg.


