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How to get fromPoughkeepsie to Walthamby train (Amtrak), bus (Greyhound, Flixbus), car, train, plane, or bus

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There are 8 ways to get from Poughkeepsie to Waltham by train (Amtrak), bus (Greyhound, Flixbus), car, train, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via New York (Amtrak)

    best
    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
    6h 16m
    $74–187

  2. Bus

    cheapest
    1. Take the bus from Metro North Station to TransCenterbus bus Wpp
    2. Take the bus from White Plains Bus Station to Hartford Union Stationbus bus
    3. Take the bus from Hartford Union Station to Bostonbus bus
    9h 51m
    $30–62

  3. Drive  170.6 mi

    1. Drive from Poughkeepsie to Walthamcar car 170.6 mi
    3h 38m
    $32–45

  4. Train to Laguardia Airport, fly

    1. Take the train from Poughkeepsie to 125th Street - Harlemtrain train
    2. Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane plane LGA - BOS
    5h 23m
    $76–436

  5. Train, bus

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train
    2. Take the bus from Pittsfield to Worcesterbus bus
    3. Take the train from Worcester to Lansdownetrain train
    9h 14m
    $58–133

  6. Train (Amtrak)

    1. Take the train from Poughkeepsie Amtrak Station to Pittsfield Amtrak Stationtrain train Berkshire Flyer
    2. Take the train from Pittsfield Amtrak Station to Bostontrain train Lake Shore Limited
    9h 17m
    $65–164

  7. Train to Newark Liberty International Airport, fly

    1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane plane EWR - BOS
    5h 27m
    $519–1,370

  8. Train to John F. Kennedy International Airport, fly

    1. Take the train from Poughkeepsie to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Boston Logan Airport (BOS)plane plane JFK - BOS
    5h 47m
    $453–1,247

Poughkeepsie to Waltham by train and bus (Amtrak)

Calendar71Weekly Services
Duration6h 16mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Poughkeepsie to Waltham.ExpandLaunch map view
  • Distance: 308.7 mi
  • Duration: 6h 16m

What companies run services between Poughkeepsie, NY, USA and Waltham, MA, USA?

You can take a train from Poughkeepsie Amtrak Station to Washington St @ Bacon St via Ny Moynihan Train Hall At Penn Station, Boston, and Saint James Ave @ Dartmouth St in around 6h 16m. Alternatively, you can take a bus from Metro North Station to Elm St @ Main St via TransCenter, White Plains Bus Station, Hartford Union Station, Boston, and Otis St @ Summer St in around 9h 51m.

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