There are 8 ways to get from Prague to Brussels-South Station by plane, train (Eurostar), bus, car, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Brussels Airport
best- Fly from Václav Havel Airport Prague (PRG) to Brussels Airport (BRU)plane PRG - BRU
4h 33m€84–240Fly to Brussels South Charleroi Airport, train
cheapest- Fly from Václav Havel Airport Prague (PRG) to Brussels South Charleroi Airport (CRL)plane PRG - CRL
- Take the train from Charleroi-Central to Bruxelles-Miditrain
5h 37m€64–256Train via Nuremberg
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nürnberg Hbf to Köln Messe/Deutz Bftrain 41 / ...
- Take the train from Koeln Hbf to Brussel-Zuid / Bruxelles-Miditrain
12h 28m€213–577Bus
- Take the bus from Praha, ÚAN Florenc to Brussels Southbus N84
15h 5m€70–140Drive 871 km
- Drive from Prague to Brussels-South Stationcar 871 km
8h 21m€133–192Fly to Amsterdam Airport Schiphol, train
- Fly from Václav Havel Airport Prague (PRG) to Amsterdam Airport Schiphol (AMS)plane PRG - AMS
- Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain
6h 11m€127–334Train
- Take the train from Praha Hlavní nádraží to Frankfurttrain Drf
- Take the train from Frankfurt to Bruxelles Miditrain 79
15h 21mBus, night train
- Take the bus from Praha Hlavní nádraží to Kölnbus Ivano-Frankivsk
- Take the nighttrain from Koeln Hbf to Brussel-Zuid / Bruxelles-Midinighttrain Nj
23h
Prague to Brussels-South Station by train and foot
Questions & Answers
The cheapest way to get from Prague to Brussels-South Station is to bus which costs €70 - €140 and takes 15h 5m.
The fastest way to get from Prague to Brussels-South Station is to fly which takes 4h 33m and costs €80 - €240.
Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Brussels South. Services depart once daily, and operate every day. The journey takes approximately 15h 5m.
No, there is no direct train from Prague to Brussels-South Station. However, there are services departing from Praha Hlavni Nadrazi and arriving at Brussel-Zuid / Bruxelles-Midi via Schwandorf, Nürnberg Hbf, Koeln Messe/Deutz and Koeln Hbf. The journey, including transfers, takes approximately 12h 28m.
The distance between Prague and Brussels-South Station is 727 km. The road distance is 871 km.
The best way to get from Prague to Brussels-South Station without a car is to train via Nuremberg which takes 12h 28m and costs €210 - €600.
It takes approximately 4h 33m to get from Prague to Brussels-South Station, including transfers.
Prague to Brussels-South Station bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Brussels-South Station train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Brussels-South Station is to fly which takes 4h 33m and costs €80 - €240. Alternatively, you can train via Nuremberg, which costs €210 - €600 and takes 12h 28m, you could also bus, which costs €70 - €140 and takes 15h 5m.
What companies run services between Prague, Czechia and Brussels-South Station, Belgium?
Smartwings, Brussels Airlines, and four other airlines fly from Václav Havel Airport Prague (PRG) to Brussels Airport (BRU) every 3 hours. Alternatively, you can take a train from Praha Hlavni Nadrazi to Brussels-South Station via Schwandorf, Nürnberg Hbf, Köln Messe/Deutz Bf, Koeln Messe/Deutz, Koeln Hbf, and Brussel-Zuid / Bruxelles-Midi in around 12h 28m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Brussels Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–190
Flights from Václav Havel Airport Prague to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- €85–490
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €110–550
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol via Munich
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €55–550
- Website
- klm.com
Flights from Václav Havel Airport Prague to Brussels Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €50–280
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- €45–270
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 33m
- When
- Tuesday, Monday, Friday, Wednesday, Thursday, and Sunday
- Estimated price
- €65–210
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Brussels Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €75–190
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Brussels Airport via Zurich
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €80–210
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Brussels South Charleroi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €45–230
- Website
- smartwings.com
Flights from Václav Havel Airport Prague to Brussels Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Saturday
- Estimated price
- €70–190
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- €50–95
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nürnberg Hbf to Köln Messe/Deutz Bf
- Ave. Duration
- 3h 14m
- Frequency
- Hourly
- Estimated price
- €70–320
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Bruxelles Midi
- Ave. Duration
- 3h 4m
- Frequency
- Every 4 hours
- Estimated price
- €70–310
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 56m
- Frequency
- Every 2 hours
- Estimated price
- €65–120
- Website
- Eurostar
Train from Schiphol Airport to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Eurostar
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Charleroi-Central to Bruxelles-Midi
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- €9–19
- Website
- Belgian Railways
Train from Frankfurt to Bruxelles Midi
- Ave. Duration
- 3h 46m
- Frequency
- 4 times a week
- Estimated price
- €65–140
- Website
- Belgian Railways
- Website
- LEO Express
Train from Praha Hlavní nádraží to Frankfurt
- Ave. Duration
- 11h 17m
- Frequency
- Once a week
- Schedules at
- LEO Express
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 2h 55m
- Frequency
- 6 times a week
- Estimated price
- €22–95
- Website
- Nightjet
- Sleeper Carriage
- €85–95
- Couchette Carriage
- €50–65
- Seating Carriage
- €22–26
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Praha, ÚAN Florenc to Brussels South
- Ave. Duration
- 15h 5m
- Frequency
- Twice daily
- Estimated price
- €80–140
- Website
- Flixbus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Praha, ÚAN Florenc to Brussels South
- Ave. Duration
- 12h
- Frequency
- 4 times a week
- Estimated price
- €70–110
- Website
- RegioJet
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Praha Hlavní nádraží to Köln
- Ave. Duration
- 18h 59m
- Frequency
- Once daily
- Website
- Grand Bus
Want to know more about travelling around Belgium
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More Questions & Answers
Prague to Brussels-South Station bus services, operated by FlixBus, arrive at Brussels South station.
Prague to Brussels-South Station train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Brussels-South Station is 871 km. It takes approximately 8h 21m to drive from Prague to Brussels-South Station.
Book your Prague to Brussels-South Station train tickets online with Omio.
Book your Prague to Brussels-South Station bus tickets online with Omio, FlixBus and Distribusion.
There are 1773+ hotels available in Brussels-South Station.

































