There are 3 ways to get from Prague to Des Moines by plane or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Václav Havel Airport Prague
best- Fly from Václav Havel Airport Prague (PRG) to Des Moines (DSM)plane PRG - DSM
16h 37m$569–2,025Train to Dresden Airport, fly
- Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Des Moines (DSM)plane DRS - DSM
19h 9m$896–3,110Train to Munich International Airport, fly
- Take the train from Praha Hlavni Nadrazi to Freisingtrain
- Fly from Munich International Airport (MUC) to Des Moines (DSM)plane MUC - DSM
20h 45m$718–2,408
Václav Havel Airport Prague (PRG) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Prague to Des Moines is to fly which costs $550 - $2,100 and takes 16h 37m.
The fastest way to get from Prague to Des Moines is to fly which takes 16h 37m and costs $550 - $2,100.
The distance between Prague and Des Moines is 4799 miles.
It takes approximately 16h 37m to get from Prague to Des Moines, including transfers.
Des Moines is 7h behind Prague. It is currently 11:42 PM in Prague and 4:42 PM in Des Moines.
There are 263+ hotels available in Des Moines.
What companies run services between Prague, Czechia and Des Moines, IA, USA?
American Airlines, Air Dolomiti, and seven other airlines fly from Václav Havel Airport Prague (PRG) to Des Moines (DSM) every 3 hours.
- Website
- united.com
Flights from Václav Havel Airport Prague to Des Moines via Munich International Airport, Chicago O'Hare
- Ave. Duration
- 14h 52m
- When
- Every day
- Estimated price
- $550–2,200
Flights from Václav Havel Airport Prague to Des Moines via Frankfurt, Chicago O'Hare
- Ave. Duration
- 15h 31m
- When
- Every day
- Estimated price
- $550–2,200
Flights from Václav Havel Airport Prague to Des Moines via Brussels, Chicago O'Hare
- Ave. Duration
- 14h 36m
- When
- Monday to Saturday
- Estimated price
- $550–2,000
Flights from Dresden Airport to Des Moines via Frankfurt, Chicago O'Hare
- Ave. Duration
- 14h 37m
- When
- Every day
- Estimated price
- $850–3,000
Flights from Dresden Airport to Des Moines via Munich International Airport, Chicago O'Hare
- Ave. Duration
- 15h 28m
- When
- Every day
- Estimated price
- $850–3,100
Flights from Munich International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 12h 45m
- When
- Every day
- Estimated price
- $600–2,400
Flights from Munich International Airport to Des Moines via Denver
- Ave. Duration
- 15h 29m
- When
- Every day
- Estimated price
- $700–2,700
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Des Moines via Frankfurt, Chicago O'Hare
- Ave. Duration
- 14h 52m
- When
- Wednesday, Friday, Sunday, Monday, and Saturday
- Estimated price
- $550–2,200
Flights from Václav Havel Airport Prague to Des Moines via Munich International Airport, Chicago O'Hare
- Ave. Duration
- 14h 52m
- When
- Every day
- Estimated price
- $550–2,200
Flights from Dresden Airport to Des Moines via Frankfurt, Chicago O'Hare
- Ave. Duration
- 13h 58m
- When
- Every day
- Estimated price
- $850–3,000
Flights from Dresden Airport to Des Moines via Munich International Airport, Chicago O'Hare
- Ave. Duration
- 15h 28m
- When
- Every day
- Estimated price
- $850–3,100
Flights from Munich International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 12h 45m
- When
- Every day
- Estimated price
- $600–2,400
- Website
- klm.com
Flights from Václav Havel Airport Prague to Des Moines via Amsterdam Schiphol, Minneapolis
- Ave. Duration
- 15h 18m
- When
- Every day
- Estimated price
- $550–2,000
Flights from Václav Havel Airport Prague to Des Moines via Reykjavik Keflavik Nas, Minneapolis
- Ave. Duration
- 13h 59m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $600–2,100
Flights from Dresden Airport to Des Moines via Frankfurt, Detroit
- Ave. Duration
- 18h 11m
- When
- Every day
- Estimated price
- $850–3,100
Flights from Munich International Airport to Des Moines via Detroit
- Ave. Duration
- 15h 11m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $600–2,200
Flights from Munich International Airport to Des Moines via Atlanta
- Ave. Duration
- 19h 12m
- When
- Every day
- Estimated price
- $700–2,500
- Website
- delta.com
Flights from Václav Havel Airport Prague to Des Moines via Amsterdam Schiphol, Minneapolis
- Ave. Duration
- 15h 18m
- When
- Every day
- Estimated price
- $550–2,000
Flights from Václav Havel Airport Prague to Des Moines via Reykjavik Keflavik Nas, Minneapolis
- Ave. Duration
- 13h 59m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $600–2,100
Flights from Dresden Airport to Des Moines via Frankfurt, Detroit
- Ave. Duration
- 18h 11m
- When
- Every day
- Estimated price
- $850–3,100
Flights from Munich International Airport to Des Moines via Detroit
- Ave. Duration
- 15h 11m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $600–2,200
Flights from Munich International Airport to Des Moines via Atlanta
- Ave. Duration
- 19h 12m
- When
- Every day
- Estimated price
- $700–2,500
- Website
- aa.com
Flights from Václav Havel Airport Prague to Des Moines via Philadelphia
- Ave. Duration
- 18h 51m
- When
- Every day
- Estimated price
- $550–2,100
Flights from Dresden Airport to Des Moines via Zurich, Chicago O'Hare
- Ave. Duration
- 16h 18m
- When
- Monday
- Estimated price
- $950–2,900
Flights from Munich International Airport to Des Moines via Charlotte
- Ave. Duration
- 14h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $650–2,400
- Phone
- +420 221 111 122
- [email protected]
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 19m
- Frequency
- Every 2 hours
- Estimated price
- $26–40
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +43 (0) 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 27m
- Frequency
- Twice daily
- Estimated price
- $45–85
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Freising
- Ave. Duration
- 5h 15m
- Frequency
- Hourly
- Estimated price
- $95–170
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Website
- leoexpress.com
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 3h 4m
- Frequency
- Once daily
- Schedules at
- leoexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide











