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How to get fromPrague to Karlsruheby bus, train, night train, car, or plane

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There are 10 ways to get from Prague to Karlsruhe by bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus bus BlaBlaCar Bus
    2. Take the train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train S3 / ...
    8h 4m
    €54–123
  2. Bus

    cheapest
    1. Take the bus from Prague to Karlsruhe central train stationbus bus N168
    8h 10m
    €45–80
  3. Train via Nuremberg

    1. Take the train from Praha Hlavni Nadrazi to Schwandorftrain train Ec
    2. Take the train from Schwandorf to Nürnberg Hbftrain train
    3. Take the train from Nuernberg Hbf to Stuttgart Hbftrain train Re
    4. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train Re
    9h 32m
    €115–349
  4. Night train

    1. Take the night train from Praha Hlavni Nadrazi to Karlsruhe Hbfnighttrain night train En
    10h 33m
    €170–310
  5. Drive 522.1 km

    1. Drive from Prague to Karlsruhecar car 522.1 km
    4h 29m
    €81–116
  6. Train

    1. Take the train from Praha Hlavni Nadrazi to Karlsruhe Hbftrain train Ec
    10h 33m
    €170–310
  7. Fly Václav Havel Airport Prague to Stuttgart Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane plane PRG - STR
    2. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    6h 40m
    €115–317
  8. Fly Václav Havel Airport Prague to Frankfurt, train

    1. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    2. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    5h 35m
    €71–264
  9. Fly Václav Havel Airport Prague to Munich International Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)plane plane PRG - MUC
    2. Take the train from München Hbf to Hauptbahnhoftrain train
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    6h 24m
    €145–484
  10. Train to Dresden Airport, fly to Frankfurt, train

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 2m
    €179–476

Prague to Karlsruhe by bus, foot, and train

Calendar9Weekly Services
Duration8h 4mAverage Duration
Ticket€54Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Karlsruhe, Germany?

You can take a train from Praha Hlavni Nadrazi to Karlsruhe Hbf via Schwandorf, Nürnberg Hbf, Nuernberg Hbf, and Stuttgart Hbf in around 9h 32m. Alternatively, FlixBus operates a bus from Prague to Karlsruhe central train station once daily. Tickets cost €45–80 and the journey takes 8h 10m.

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