There are 11 ways to get from Prague to Karlsruhe by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus BlaBlaCar Bus
- Take the train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain Re73 / ...
7h 41m€42–94Train via Nuremberg
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nuernberg Hbf to Stuttgart Hbftrain Re
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain Re
9h 6m€93–260Night train
- Take the nighttrain from Praha Hlavni Nadrazi to Karlsruhe Hbfnighttrain En
10h 33m€160–290Drive 522.1 km
- Drive from Prague to Karlsruhecar 522.1 km
4h 30m€83–120Bus
- Take the bus from Prague to Karlsruhe central train stationbus N168
8h 10m€45–75Train
- Take the train from Praha Hlavni Nadrazi to Karlsruhe Hbftrain Ec
10h 33m€120–200Fly Václav Havel Airport Prague to Stuttgart Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane PRG - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
6h 39m€118–338Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
5h 35m€71–164Fly Václav Havel Airport Prague to Munich International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)plane PRG - MUC
- Take the train from München Hbf to Hauptbahnhoftrain
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
6h 38m€146–392Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 12m€161–396Fly Václav Havel Airport Prague to Basel, train
- Fly from Václav Havel Airport Prague (PRG) to Basel (BSL)plane PRG - BSL
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
6h 22m€98–310
Prague to Karlsruhe by bus and train
Comparing Your Travel Options
The cheapest way to get from Prague to Karlsruhe is to bus which costs €45 - €75 and takes 8h 10m.
The fastest way to get from Prague to Karlsruhe is to drive which takes 4h 30m and costs €80 - €120.
Yes, there is a direct bus departing from Prague and arriving at Karlsruhe central train station station. Services depart four times a week, and operate every day. The journey takes approximately 8h 10m.
Yes, there is an overnight train departing from Praha Hlavni Nadrazi and arriving at Karlsruhe Hbf. This train operates every day. The journey takes approximately 10h 33m.
The distance between Prague and Karlsruhe is 554 km. The road distance is 522.1 km.
The best way to get from Prague to Karlsruhe without a car is to bus and train which takes 7h 41m and costs €40 - €95.
It takes approximately 7h 41m to get from Prague to Karlsruhe, including transfers.
Prague to Karlsruhe bus services, operated by FlixBus, depart from Prague station.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Karlsruhe is to train via Nuremberg which takes 9h 6m and costs €90 - €260. Alternatively, you can bus, which costs €45 - €75 and takes 8h 10m.
What companies run services between Prague, Czechia and Karlsruhe, Germany?
You can take a train from Praha Hlavni Nadrazi to Karlsruhe Hbf via Schwandorf, Nürnberg Hbf, Nuernberg Hbf, and Stuttgart Hbf in around 9h 6m. Alternatively, FlixBus operates a bus from Prague to Karlsruhe central train station 4 times a week. Tickets cost €45–75 and the journey takes 8h 10m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Munich International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €90–330
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–360
Flights from Václav Havel Airport Prague to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €60–130
Flights from Václav Havel Airport Prague to Munich International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €80–300
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €45–340
Flights from Dresden Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- €140–290
Flights from Václav Havel Airport Prague to Basel via Munich International Airport
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- €85–460
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 26m
- When
- Every day
- Estimated price
- €85–340
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €55–110
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Vienna
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–340
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Basel
- Ave. Duration
- 1h 20m
- When
- Sunday, Monday, Wednesday, and Friday
- Estimated price
- €40–220
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–360
- Website
- lufthansa-city.com
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €45–340
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 34 min
- Frequency
- Every 30 minutes
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €15–70
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 40 min
- Frequency
- 5 times a day
- Estimated price
- €10–20
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 56m
- Frequency
- 3 times a day
- Estimated price
- €35–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from München Hbf to Hauptbahnhof
- Ave. Duration
- 2h 15m
- Frequency
- Every 30 minutes
- Estimated price
- €40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- Österreichische Bundesbahnen
- Phone
- +49 6131 4975 022
- [email protected]
- Website
- dbregiobus-mitte.de
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Once a week
- Estimated price
- €12–17
- Schedules at
- dbregiobus-mitte.de
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Karlsruhe Hbf
- Ave. Duration
- 10h 33m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- €29–50
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 28m
- Frequency
- Hourly
- Estimated price
- €29–55
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €29–35
- 1st Class Ticket
- €35–55
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Nuernberg Hbf to Stuttgart Hbf
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €26–40
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Praha Hlavni Nadrazi to Karlsruhe Hbf
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- €160–290
- Website
- Austrian Railways
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
Train from München Hbf to Hauptbahnhof
- Ave. Duration
- 1h 59m
- Frequency
- Once daily
- Estimated price
- €25–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 19m
- Frequency
- Every 3 hours
- Estimated price
- €15
- Website
- Czech Railways (ČD)
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Prague - Florenc Main Bus Terminal to Heidelberg
- Ave. Duration
- 6h 55m
- Frequency
- 3 times a day
- Estimated price
- €30–55
- Website
- BlaBlaCar Bus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Karlsruhe central train station
- Ave. Duration
- 8h 10m
- Frequency
- 4 times a week
- Estimated price
- €45–75
- Website
- Flixbus
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Booking & Getting There
Prague to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Karlsruhe is 522 km. It takes approximately 4h 30m to drive from Prague to Karlsruhe.
Book your Prague to Karlsruhe train tickets online with Omio.
Book your Prague to Karlsruhe bus tickets online with Omio and FlixBus.
There are 899+ hotels available in Karlsruhe.














































