There are 11 ways to get from Prague to Karlsruhe by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train via Nuremberg
best- Take the bus from Prague to Nuremberg central bus stationbus N1309 / ...
- Take the train from Nürnberg Hbf to Karlsruhe Hauptbahnhoftrain 61
7h 32m€71–128Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Karlsruhe central train stationbus N1315 / ...
8h 40m€50–75Train via Nuremberg
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nürnberg Hbf to Karlsruhe Hauptbahnhoftrain 61
9h 32m€118–168Night train
- Take the nighttrain from Praha Hlavni Nadrazi to Karlsruhe Hbfnighttrain En
10h 33m€140–250Drive 522.1 km
- Drive from Prague to Karlsruhecar 522.1 km
4h 30m€97–141Train
- Take the train from Praha Hlavni Nadrazi to Karlsruhe Hbftrain Ec
11h 30m€211Bus, train
- Take the bus from Praha Hlavní nádraží to Stuttgartbus Ivano-Frankivsk
- Take the train from Hauptbahnhof to Wilferdingen-Singen Bahnhoftrain Re1
11h 55m€85–107Fly Václav Havel Airport Prague to Stuttgart Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane PRG - STR
- Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
6h 41m€113–314Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
5h 40m€78–169Fly Václav Havel Airport Prague to Basel, train
- Fly from Václav Havel Airport Prague (PRG) to Basel (BSL)plane PRG - BSL
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
6h 14m€79–340Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h€157–385
Prague to Karlsruhe by bus and train
Comparing Your Travel Options
The cheapest way to get from Prague to Karlsruhe is to bus which costs €50 - €75 and takes 8h 40m.
The fastest way to get from Prague to Karlsruhe is to drive which takes 4h 30m and costs €95 - €140.
Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Karlsruhe central train station station. Services depart every four hours, and operate every day. The journey takes approximately 8h 40m.
Yes, there is an overnight train departing from Praha Hlavni Nadrazi and arriving at Karlsruhe Hbf. This train operates every day. The journey takes approximately 10h 33m.
The distance between Prague and Karlsruhe is 569 km. The road distance is 522.1 km.
The best way to get from Prague to Karlsruhe without a car is to bus and train via Nuremberg which takes 7h 32m and costs €70 - €130.
It takes approximately 7h 32m to get from Prague to Karlsruhe, including transfers.
Prague to Karlsruhe bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Karlsruhe is to train via Nuremberg which takes 9h 32m and costs €110 - €170. Alternatively, you can bus, which costs €50 - €75 and takes 8h 40m.
What companies run services between Prague, Czechia and Karlsruhe, Germany?
You can take a train from Praha Hlavni Nadrazi to Karlsruhe Hauptbahnhof via Schwandorf, Nürnberg Hbf, and Nürnberg Hbf in around 9h 32m. Alternatively, FlixBus operates a bus from Praha, ÚAN Florenc to Karlsruhe central train station every 4 hours. Tickets cost €50–75 and the journey takes 8h 40m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Monday to Saturday
- Estimated price
- €95–350
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–390
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €60–140
Flights from Václav Havel Airport Prague to Basel via Munich
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €100–490
Flights from Václav Havel Airport Prague to Basel via Frankfurt
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- €100–500
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €50–340
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Vienna
- Ave. Duration
- 3h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–360
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €55–120
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €85–350
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–390
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Basel
- Ave. Duration
- 1h 20m
- When
- Monday, Friday, and Sunday
- Estimated price
- €40–220
- Website
- lufthansa-city.com
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €50–340
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nürnberg Hbf to Karlsruhe Hauptbahnhof
- Ave. Duration
- 3h 13m
- Frequency
- Every 4 hours
- Estimated price
- €45–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nürnberg Hbf to Karlsruhe Hauptbahnhof
- Ave. Duration
- 3h 13m
- Frequency
- Every 4 hours
- Estimated price
- €45–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €12–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- €64
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Karlsruhe Hbf
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €211
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €48
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hauptbahnhof to Wilferdingen-Singen Bahnhof
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €7–10
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Praha Hlavni Nadrazi to Karlsruhe Hbf
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- €140–250
- Website
- Austrian Railways
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Hauptbahnhof to Wilferdingen-Singen Bahnhof
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- €12–17
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Hauptbahnhof to Wilferdingen-Singen Bahnhof
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €12–23
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €12–15
- 1st Class Ticket
- €16–23
Train from Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €19–27
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 58m
- Frequency
- 3 times a day
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €45–95
- Website
- Trenitalia Eurocity
- 1st Class
- €65–95
- 2nd Class
- €45–65
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 7m
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Website
- Czech Railways (ČD)
- Phone
- +47 70 13 14 15
- [email protected]
- Website
- Danish Railways
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €15
- Website
- Danish Railways
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Nuremberg central bus station
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Flixbus
Bus from Praha, ÚAN Florenc to Karlsruhe central train station
- Ave. Duration
- 8h 40m
- Frequency
- Every 4 hours
- Estimated price
- €50–75
- Website
- Flixbus
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Praha Hlavní nádraží to Stuttgart
- Ave. Duration
- 10h 1m
- Frequency
- Once daily
- Estimated price
- €75–85
- Website
- Grand Bus
Want to know more about travelling around Germany
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Booking & Getting There
Prague to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Karlsruhe is 522 km. It takes approximately 4h 30m to drive from Prague to Karlsruhe.
Book your Prague to Karlsruhe train tickets online with Omio and 12go.asia.
Book your Prague to Karlsruhe bus tickets online with Omio, FlixBus and 12go.asia.
There are 897+ hotels available in Karlsruhe.
















































