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How to get fromPrague to Karlsruheby bus, train, night train, car, or plane

Find Transport to Karlsruhe

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There are 10 ways to get from Prague to Karlsruhe by bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Prague to Karlsruhe central train stationbus bus N168
    8h 10m
    €50–75

  2. Train via Erfurt

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train Rj
    2. Take the train from Dresden Hauptbahnhof to Leipzig Hbftrain train 55 / ...
    3. Take the train from Leipzig Hbf to Erfurt Hbftrain train 28 / ...
    4. Take the train from Erfurt Hbf to Frankfurttrain train 12 / ...
    5. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train 12 / ...
    8h 50m
    €117–343

  3. Night train

    1. Take the nighttrain from Praha Hlavni Nadrazi to Karlsruhe Hbfnighttrain night train En
    10h 33m
    €160–260

  4. Drive  522.1 km

    1. Drive from Prague to Karlsruhecar car 522.1 km
    4h 30m
    €83–120

  5. Train

    1. Take the train from Praha Hlavni Nadrazi to Karlsruhe Hbftrain train Ec
    11h 31m
    €190–220

  6. Bus, train

    1. Take the bus from Praha Hlavní nádraží to Stuttgartbus bus Ivano-Frankivsk
    2. Take the train from Hauptbahnhof to Wilferdingen-Singen Bahnhoftrain train Re1
    11h 56m
    €89–133

  7. Fly Václav Havel Airport Prague to Stuttgart Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane plane PRG - STR
    2. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    6h 41m
    €118–354

  8. Fly Václav Havel Airport Prague to Frankfurt, train

    1. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    2. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    5h 40m
    €71–164

  9. Fly Václav Havel Airport Prague to Basel, train

    1. Fly from Václav Havel Airport Prague (PRG) to Basel (BSL)plane plane PRG - BSL
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    6h 14m
    €88–385

  10. Train to Dresden Airport, fly to Frankfurt, train

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h
    €151–400

Prague to Karlsruhe by bus

Calendar4Weekly Buses
Duration8h 10mAverage Duration
Ticket€50Cheapest Price
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Comparing Your Travel Options

Map of how to get from Prague to Karlsruhe.ExpandLaunch map view
  • Distance: 572.6 km
  • Duration: 8h 10m

What companies run services between Prague, Czechia and Karlsruhe, Germany?

FlixBus operates a bus from Prague to Karlsruhe central train station 4 times a week. Tickets cost €50–75 and the journey takes 8h 10m. Alternatively, you can take a train from Praha-Holesovice to Karlsruhe Hauptbahnhof via Dresden Hauptbahnhof, Leipzig Hbf, Erfurt Hbf, and Frankfurt in around 8h 50m.

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