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How to get fromPrague to Madridby plane, train, bus, car, or night train

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There are 8 ways to get from Prague to Madrid by plane, train, bus, car, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Václav Havel Airport Prague

    best
    1. Fly from Václav Havel Airport Prague (PRG) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PRG - MAD
    5h 57m
    €68–206
  2. Train, bus

    1. Take the train from Praha Hlavni Nadrazi to Schwandorftrain train Ec
    2. Take the train from Schwandorf to Nürnberg Hbftrain train
    3. Take the bus from Nuremberg central bus station to Mulhousebus bus
    4. Take the train from Mulhouse Ville to Lyon Part Dieutrain train Tgv
    5. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    6. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    25h 8m
    €305–585
  3. Bus, train via Barcelona

    1. Take the bus from Prague Florenc Central Bus Station to Lyon Perrache Bus Stationbus bus
    2. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    3. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    25h 13m
    €195–382
  4. Drive  2,186.2 km

    1. Drive from Prague to Madridcar car 2,186.2 km
    20h 36m
    €358–517
  5. Train to Dresden Airport, fly

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane DRS - MAD
    9h 47m
    €168–462
  6. Bus, train

    1. Take the bus from Praha, ÚAN Florenc to Marseille, Gare de Marseille-Saint-Charlesbus bus N1759 / ...
    2. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train 9730
    30h 9m
    €266–396
  7. Bus

    1. Take the bus from Prague Florenc Central Bus Station to Strasbourg Central Bus Station Place de l’Etoilebus bus : Paris Bercy Central Bus Station - Prague Central Bus Station / ...
    2. Take the bus from Strasbourg - L'Étoile Park Bus Station to Estación Sur de Autobusesbus bus BlaBlaCar Bus
    33h 25m
    €169–292
  8. Train, night train, bus

    1. Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain train Ec
    2. Take the nighttrain from Linz/Donau Hbf to Treviso Centralenighttrain night train Nj
    3. Take the bus from Treviso to Padovabus bus 101
    4. Take the bus from Padova to Méndez Álvaro Estación Surbus bus
    43h 31m
    €182–351

Prague to Madrid by train, foot, and bus

Calendar7Weekly Services
Duration25h 8mAverage Duration
Ticket€305Cheapest Price
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Comparing Your Travel Options

What companies run services between Prague, Czechia and Madrid, Spain?

Ryanair, Smartwings, and four other airlines fly from Václav Havel Airport Prague (PRG) to Adolfo Suárez Madrid–Barajas Airport (MAD) every 4 hours. Alternatively, you can take a bus from Prague Florenc Central Bus Station to Estación Sur de Autobuses via Strasbourg - L'Étoile Park Bus Station in around 33h 25m.

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