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How to get fromPrague to Mainzby subway, plane, bus, train, or car

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There are 7 ways to get from Prague to Mainz by subway, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Václav Havel Airport Prague, fly

    best
    1. Take the subway from Staroměstská to Nádraží Veleslavínsubway subway
    2. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    4h 1m
    €63–127

  2. Bus

    cheapest
    1. Take the bus from Praha, Hlavní Nádraží to Mainz central train stationbus bus N1310
    8h 35m
    €40–70

  3. Train via Nuremberg

    1. Take the train from Praha Hlavni Nadrazi to Schwandorftrain train Ec
    2. Take the train from Schwandorf to Nürnberg Hbftrain train
    3. Take the train from Nürnberg Hbf to Frankfurttrain train 41 / ...
    8h 48m
    €124–312

  4. Drive 539.5 km

    1. Drive from Prague to Mainzcar car 539.5 km
    4h 28m
    €84–121

  5. Train to Dresden Airport, fly

    1. Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    5h 38m
    €162–379

  6. Train

    1. Take the train from Praha Hlavní nádraží to Frankfurttrain train Drf
    11h 50m

  7. Bus via Frankfurt am Main

    1. Take the bus from Praha Hlavní nádraží to Frankfurt, Hauptbahnhof FOBbus bus Ivano-Frankivsk
    17h 49m
    €131–146

Prague to Mainz by bus

Calendar7Weekly Buses
Duration8h 35mAverage Duration
Ticket€40Cheapest Price
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Questions & Answers

Map of how to get from Prague to Mainz.ExpandLaunch map view
  • Distance: 446.7 km
  • Duration: 4h 1m

What companies run services between Prague, Czechia and Mainz, Germany?

FlixBus operates a bus from Praha, Hlavní Nádraží to Mainz central train station once daily. Tickets cost €40–70 and the journey takes 8h 35m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mainz, Römisches Theater via Schwandorf, Nürnberg Hbf, and Frankfurt in around 8h 48m.

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