There are 7 ways to get from Prague to Mainz-Kastel by subway, plane, bus, train, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Václav Havel Airport Prague, fly
best- Take the subway from Staroměstská to Nádraží Veleslavínsubway
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
4h 13m€62–150Bus
cheapest- Take the bus from Praha, Hlavní Nádraží to Mainz central train stationbus N1310
8h 54m€50–75Train via Schwandorf
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nürnberg Hbf to Frankfurttrain 41 / ...
8h 58m€125–268Night train, train
- Take the nighttrain from Praha Hlavni Nadrazi to Hanau Hbfnighttrain En
- Take the train from Hanau Hauptbahnhof to Wiesbaden-Mainz-Kastel Bahnhoftrain S9
10h 27m€138–262Train to Dresden Airport, fly
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
5h 33m€143–378Train
- Take the train from Praha Hlavni Nadrazi to Hanau Hbftrain Ec
- Take the train from Hanau Hauptbahnhof to Wiesbaden-Mainz-Kastel Bahnhoftrain S9
10h 27m€183–230Drive 539.9 km
- Drive from Prague to Mainz-Kastelcar 539.9 km
4h 31m€102–147
Prague to Mainz-Kastel by bus
Comparing Your Travel Options
The cheapest way to get from Prague to Mainz-Kastel is to bus which costs €50 - €75 and takes 8h 54m.
The fastest way to get from Prague to Mainz-Kastel is to subway and fly which takes 4h 13m and costs €60 - €150.
No, there is no direct bus from Prague to Mainz-Kastel. However, there are services departing from Praha, Hlavní Nádraží and arriving at Wiesbaden-Mainz-Kastel Bahnhof via Mainz, Hbf West/Taubertsbergb.. The journey, including transfers, takes approximately 8h 54m.
No, there is no direct train from Prague to Mainz-Kastel. However, there are services departing from Praha Hlavni Nadrazi and arriving at Wiesbaden-Mainz-Kastel Bahnhof via Schwandorf, Nürnberg Hbf and Frankfurt. The journey, including transfers, takes approximately 8h 58m.
The distance between Prague and Mainz-Kastel is 447 km. The road distance is 539.9 km.
The best way to get from Prague to Mainz-Kastel without a car is to bus which takes 8h 54m and costs €50 - €75.
It takes approximately 4h 13m to get from Prague to Mainz-Kastel, including transfers.
Prague to Mainz-Kastel bus services, operated by FlixBus, depart from Praha, Hlavní Nádraží station.
Prague to Mainz-Kastel train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mainz-Kastel is to bus which takes 8h 54m and costs €50 - €75. Alternatively, you can train via Schwandorf, which costs €120 - €270 and takes 8h 58m.
What companies run services between Prague, Czechia and Mainz-Kastel, Hesse, Germany?
FlixBus operates a bus from Praha, Hlavní Nádraží to Mainz central train station once daily. Tickets cost €50–75 and the journey takes 8h 35m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Wiesbaden-Mainz-Kastel Bahnhof via Schwandorf, Nürnberg Hbf, and Frankfurt in around 8h 58m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–390
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €60–140
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €50–340
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €55–120
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–390
- Website
- lufthansa-city.com
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €50–340
- Phone
- +420 234 704 560
- [email protected]
- Website
- pid
Subway from Staroměstská to Nádraží Veleslavín
- Ave. Duration
- 9 min
- Frequency
- Every 10 minutes
- Estimated price
- €1–2
- Website
- pid
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- €64
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €48
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Hanau Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Twice daily
- Estimated price
- €170
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €20–90
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hanau Hauptbahnhof to Wiesbaden-Mainz-Kastel Bahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Hanau Hauptbahnhof to Wiesbaden-Mainz-Kastel Bahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nürnberg Hbf to Frankfurt
- Ave. Duration
- 2h 44m
- Frequency
- Every 30 minutes
- Estimated price
- €35–80
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Praha Hlavni Nadrazi to Hanau Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Twice daily
- Estimated price
- €120–210
- Website
- Austrian Railways
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 7m
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Website
- Czech Railways (ČD)
- Phone
- +47 70 13 14 15
- [email protected]
- Website
- Danish Railways
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €15
- Website
- Danish Railways
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Praha, Hlavní Nádraží to Mainz central train station
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- Flixbus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Prague to Mainz-Kastel bus services, operated by FlixBus, arrive at Mainz central train station.
Prague to Mainz-Kastel train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Mainz-Kastel is 540 km. It takes approximately 4h 31m to drive from Prague to Mainz-Kastel.
Book your Prague to Mainz-Kastel train tickets online with Omio.
Book your Prague to Mainz-Kastel bus tickets online with Omio.
There are 1236+ hotels available in Mainz-Kastel.






































