There are 9 ways to get from Prague to Mannheim by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Prague to Mannheim central bus stationbus N1309 / ...
6h 20m€40–70Train via Nuremberg
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nürnberg Hbf to Frankfurttrain 41 / ...
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain 12 / ...
8h 49m€130–379Night train
- Take the nighttrain from Praha Hlavni Nadrazi to Mannheim Hbfnighttrain En
9h 49m€150–280Drive 512.2 km
- Drive from Prague to Mannheimcar 512.2 km
4h 27m€78–113Bus via Heidelberg, Hauptbahnhof
- Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus BlaBlaCar Bus
7h 42m€49–85Train
- Take the train from Praha Hlavni Nadrazi to Mannheim Hbftrain Ec
9h 49m€160–290Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
4h 22m€65–204Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 49m€163–417Fly Václav Havel Airport Prague to Munich International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)plane PRG - MUC
- Take the train from München Hbf to Mannheim, Hauptbahnhoftrain
6h 13m€141–510
Prague to Mannheim by bus
Questions & Answers
The cheapest way to get from Prague to Mannheim is to bus which costs €40 - €70 and takes 6h 20m.
The fastest way to get from Prague to Mannheim is to fly and train which takes 4h 22m and costs €65 - €210.
Yes, there is a direct bus departing from Prague and arriving at Mannheim central bus station station. Services depart three times a day, and operate every day. The journey takes approximately 6h 20m.
Yes, there is an overnight train departing from Praha Hlavni Nadrazi and arriving at Mannheim Hbf. This train operates every day. The journey takes approximately 9h 49m.
The distance between Prague and Mannheim is 512 km. The road distance is 512.2 km.
The best way to get from Prague to Mannheim without a car is to bus which takes 6h 20m and costs €40 - €70.
The bus from Prague to Mannheim central bus station takes 6h 20m including transfers and departs three times a day.
Prague to Mannheim bus services, operated by FlixBus, depart from Prague station.
Prague to Mannheim train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mannheim is to bus which takes 6h 20m and costs €40 - €70. Alternatively, you can train via Nuremberg, which costs €130 - €380 and takes 8h 49m.
What companies run services between Prague, Czechia and Mannheim, Germany?
FlixBus operates a bus from Prague to Mannheim central bus station 3 times a day. Tickets cost €40–70 and the journey takes 6h 20m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mannheim, Hauptbahnhof via Schwandorf, Nürnberg Hbf, and Frankfurt in around 8h 49m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–400
Flights from Václav Havel Airport Prague to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €60–170
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–280
Flights from Dresden Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 57m
- When
- Every day
- Estimated price
- €120–280
Flights from Václav Havel Airport Prague to Munich International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €80–290
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €55–140
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €120–400
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- €50–95
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- Once daily
- Estimated price
- €160–290
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €22–40
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €19–35
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nürnberg Hbf to Frankfurt
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €40–180
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 44m
- Frequency
- Hourly
- Estimated price
- €60–280
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- Twice daily
- Estimated price
- €150–280
- Website
- Austrian Railways
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–17
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–17
- Website
- Nederlandse Spoorwegen (NS)
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 44m
- Frequency
- Once daily
- Estimated price
- €35–80
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Every 2 hours
- Estimated price
- €22–35
- Website
- Czech Railways (ČD)
- Phone
- +47 70 13 14 15
- [email protected]
- Website
- Danish Railways
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- 4 times a day
- Estimated price
- €35–55
- Website
- Danish Railways
- Phone
- +49 221 800 20 80
- [email protected]
- Website
- MSM Partyzug
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 3h 16m
- Frequency
- Once a week
- Schedules at
- MSM Partyzug
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Mannheim central bus station
- Ave. Duration
- 6h 20m
- Frequency
- 3 times a day
- Estimated price
- €40–70
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Prague - Florenc Main Bus Terminal to Heidelberg
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- €40–80
- Website
- BlaBlaCar Bus
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More Questions & Answers
Prague to Mannheim bus services, operated by FlixBus, arrive at Mannheim central bus station.
Prague to Mannheim train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Mannheim is 512 km. It takes approximately 4h 27m to drive from Prague to Mannheim.
Book your Prague to Mannheim train tickets online with Omio.
Book your Prague to Mannheim bus tickets online with Omio and FlixBus.
There are 1504+ hotels available in Mannheim.


















































