There are 10 ways to get from Prague to Medzilaborce by train, bus, night train, car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Praha Hlavni Nadrazi to Kosicetrain Ic
- Take the train from Kosice to Humennetrain 681
- Take the train from Humenne to Medzilaborce Mestotrain Re
12h 26m€49–138Night train, train
cheapest- Take the night train from Praha Hlavni Nadrazi to Humennenighttrain En
- Take the train from Humenne to Medzilaborce Mestotrain Re / ...
14h 10m€41–147Bus
- Take the bus from Praha, ÚAN Florenc to Prešovbus 915
- Take the bus from Prešov Station to Humennébus
- Take the bus from Humenné to Medzilaborce - SADbus
14h 47m€57–92Drive 678.2 km
- Drive from Prague to Medzilaborcecar 678.2 km
8h 11m€105–151Train via Prešov
- Take the train from Praha Hlavni Nadrazi to Presovtrain
- Take the train from Presov to Humennetrain Re
- Take the train from Humenne to Medzilaborce Mestotrain Re
13h 41m€46–77Fly Václav Havel Airport Prague to Rzeszów–Jasionka Airport, drive
- Fly from Václav Havel Airport Prague (PRG) to Rzeszów–Jasionka Airport (RZE)plane PRG - RZE
- Drive from Rzeszow-Airport-RZE to Medzilaborcecar
8h 15m€102–304Fly Václav Havel Airport Prague to Košice International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Košice International Airport (KSC)plane PRG - KSC
- Take the train from Kosice to Humennetrain
- Take the train from Humenne to Medzilaborce Mestotrain
8h 29m€64–250Fly Václav Havel Airport Prague to John Paul Ii International Airport Kraków–Balice, bus, drive
- Fly from Václav Havel Airport Prague (PRG) to John Paul Ii International Airport Kraków–Balice (KRK)plane PRG - KRK
- Take the bus from Kraków, Dworzec Autobusowy MDA to Rymanówbus
- Drive from Rymanów to Medzilaborcecar
9h 39m€55–196Train to Vienna International Airport, fly to Košice International Airport, train
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Košice International Airport (KSC)plane VIE - KSC
- Take the train from Kosice to Humennetrain
- Take the train from Humenne to Medzilaborce Mestotrain
11h 16m€114–353Fly Václav Havel Airport Prague to Budapest Ferenc Liszt International Airport, shuttle, train
- Fly from Václav Havel Airport Prague (PRG) to Budapest Ferenc Liszt International Airport (BUD)plane PRG - BUD
- Take a shuttle bus from Budapest Airport to Košice
- Take the train from Kosice to Humennetrain
- Take the train from Humenne to Medzilaborce Mestotrain
11h 6m€83–212
Prague to Medzilaborce by train
Questions & Answers
The cheapest way to get from Prague to Medzilaborce is to train via Prešov which costs €45 - €80 and takes 13h 41m.
The fastest way to get from Prague to Medzilaborce is to drive which takes 8h 11m and costs €100 - €150.
No, there is no direct bus from Prague to Medzilaborce. However, there are services departing from Praha, ÚAN Florenc and arriving at Medzilaborce - SAD via Prešov Station and Humenné. The journey, including transfers, takes approximately 14h 47m.
No, there is no direct train from Prague to Medzilaborce. However, there are services departing from Praha Hlavni Nadrazi and arriving at Medzilaborce Mesto via Kosice and Humenne. The journey, including transfers, takes approximately 12h 26m.
The distance between Prague and Medzilaborce is 837 km. The road distance is 678.2 km.
The best way to get from Prague to Medzilaborce without a car is to train which takes 12h 26m and costs €45 - €140.
It takes approximately 12h 26m to get from Prague to Medzilaborce, including transfers.
Prague to Medzilaborce bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Medzilaborce train services, operated by RegioJet, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Medzilaborce is to train which takes 12h 26m and costs €45 - €140. Alternatively, you can bus, which costs €55 - €95 and takes 14h 47m.
What companies run services between Prague, Czechia and Medzilaborce, Presov, Slovakia?
You can take a train from Praha Hlavni Nadrazi to Medzilaborce Mesto via Kosice and Humenne in around 12h 26m. Alternatively, you can take a bus from Praha, ÚAN Florenc to Medzilaborce - SAD via Prešov, Prešov Station, and Humenné in around 14h 47m.
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Košice International Airport via Vienna International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- €95–350
Flights from Václav Havel Airport Prague to John Paul Ii International Airport Kraków–Balice via Vienna International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €65–250
Flights from Vienna International Airport to Košice International Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €80–350
Flights from Václav Havel Airport Prague to Budapest Ferenc Liszt International Airport via Vienna International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €55–220
- Website
- lot.com
Flights from Václav Havel Airport Prague to Rzeszów–Jasionka Airport via Warsaw Chopin
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €95–350
Flights from Václav Havel Airport Prague to John Paul Ii International Airport Kraków–Balice via Warsaw Chopin
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €85–140
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Rzeszów–Jasionka Airport via Zadar
- Ave. Duration
- 5h 25m
- When
- Sunday
- Estimated price
- €65–250
Flights from Václav Havel Airport Prague to Košice International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–210
Flights from Václav Havel Airport Prague to John Paul Ii International Airport Kraków–Balice
- Ave. Duration
- 1h 10m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- €27–130
Flights from Václav Havel Airport Prague to Budapest Ferenc Liszt International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Saturday
- Estimated price
- €35–110
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to John Paul Ii International Airport Kraków–Balice via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €120–230
Flights from Vienna International Airport to Košice International Airport
- Ave. Duration
- 50 min
- When
- Every day
- Estimated price
- €80–350
Flights from Václav Havel Airport Prague to Budapest Ferenc Liszt International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €70–260
- Phone
- +420 222 222 221
- [email protected]
- Website
- regiojet.com
Train from Praha Hlavni Nadrazi to Kosice
- Ave. Duration
- 8h 27m
- Frequency
- Every 4 hours
- Estimated price
- €40–70
- Website
- https://regiojet.com/
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- Every 4 hours
- Estimated price
- €24–40
- Website
- https://regiojet.com/
- Phone
- +420 221 111 122
- [email protected]
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Kosice
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- €80–130
- Website
- https://www.cd.cz/en/default.htm
Night train from Praha Hlavni Nadrazi to Humenne
- Ave. Duration
- 12h 13m
- Frequency
- Twice daily
- Estimated price
- €95–150
- Website
- https://www.cd.cz/en/default.htm
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €45–75
- Website
- https://www.cd.cz/en/default.htm
- Phone
- +421 24 48 58 188
- [email protected]
- Website
- zssk.sk
Train from Kosice to Humenne
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €4–9
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
Night train from Praha Hlavni Nadrazi to Humenne
- Ave. Duration
- 12h 13m
- Frequency
- Once daily
- Estimated price
- €35–70
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
Train from Presov to Humenne
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- €3–7
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
Train from Kosice to Humenne
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €4–9
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
Train from Kosice to Humenne
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €4–9
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
Train from Kosice to Humenne
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €4–9
- Website
- https://www.zssk.sk/en/
Train from Humenne to Medzilaborce Mesto
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €2–4
- Website
- https://www.zssk.sk/en/
- Phone
- +420 220 311 700
- [email protected]
- Website
- leoexpress.com
Train from Praha Hlavni Nadrazi to Presov
- Ave. Duration
- 9h 36m
- Frequency
- 4 times a day
- Estimated price
- €40–70
- Website
- https://www.leoexpress.com/en
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Praha, ÚAN Florenc to Prešov
- Ave. Duration
- 9h 50m
- Frequency
- 5 times a week
- Estimated price
- €55–90
- Website
- https://www.flixbus.co.uk
- Phone
- +421 57 7863 103
- [email protected]
- Website
- sadhe.sk
Bus from Prešov Station to Humenné
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- €1
- Schedules at
- sadhe.sk
Bus from Humenné to Medzilaborce - SAD
- Ave. Duration
- 1h 12m
- Frequency
- Every 2 hours
- Estimated price
- €1
- Schedules at
- sadhe.sk
- Phone
- 605 935 521
- [email protected]
- Website
- sanbus.pl
Bus from Kraków, Dworzec Autobusowy MDA to Rymanów
- Ave. Duration
- 3h 11m
- Frequency
- Hourly
- Estimated price
- €13–15
- Schedules at
- sanbus.pl
- Phone
- +36 70 282 1827
- [email protected]
- Website
- eurobusways.com
Shuttle from Budapest Airport to Košice
- Ave. Duration
- 3h
- Frequency
- On demand
- Estimated price
- €35–65
- Schedules at
- eurobusways.com
Want to know more about travelling around Slovakia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Want to know more about Flixbus?
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
More Questions & Answers
Prague to Medzilaborce bus services, operated by FlixBus, arrive at Prešov station.
Prague to Medzilaborce train services, operated by RegioJet, arrive at Kosice station.
Yes, the driving distance between Prague to Medzilaborce is 678 km. It takes approximately 8h 11m to drive from Prague to Medzilaborce.
Book your Prague to Medzilaborce train tickets online with Omio.
There are 82+ hotels available in Medzilaborce.























