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How to get fromPrague to Medzilaborceby train, bus, night train, car, or plane

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There are 8 ways to get from Prague to Medzilaborce by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Praha Hlavni Nadrazi to Kosicetrain train Ic
    2. Take the train from Kosice to Humennetrain train 681
    3. Take the train from Humenne to Medzilaborce Mestotrain train Re
    13h 7m
    €45–261

  2. Night train, train

    cheapest
    1. Take the nighttrain from Praha hl.n. to Humennénighttrain night train En 443 / ...
    2. Take the train from Humenne to Medzilaborce Mestotrain train Re / ...
    14h 26m
    €41–138

  3. Bus

    1. Take the bus from Praha, ÚAN Florenc to Prešovbus bus 915
    2. Take the bus from Prešov Station to Humennébus bus
    3. Take the bus from Humenné to Medzilaborce - SADbus bus
    14h 47m
    €54–85

  4. Drive  677.7 km

    1. Drive from Prague to Medzilaborcecar car 677.7 km
    8h 5m
    €105–152

  5. Train, bus

    1. Take the train from Praha hl.n. to Prešovtrain train
    2. Take the bus from Prešov Station to Humennébus bus
    3. Take the bus from Humenné to Medzilaborce - SADbus bus
    14h 33m
    €43–62

  6. Fly to Rzeszów–Jasionka Airport, drive

    1. Fly from Václav Havel Airport Prague (PRG) to Rzeszów–Jasionka Airport (RZE)plane plane PRG - RZE
    2. Drive from Rzeszow-Airport-RZE to Medzilaborcecar car
    8h 15m
    €113–309

  7. Fly to Košice International Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Košice International Airport (KSC)plane plane PRG - KSC
    2. Take the train from Kosice to Humennetrain train
    3. Take the train from Humenne to Medzilaborce Mestotrain train
    9h 10m
    €64–270

  8. Fly to John Paul Ii International Airport Kraków–Balice, bus, drive

    1. Fly from Václav Havel Airport Prague (PRG) to John Paul Ii International Airport Kraków–Balice (KRK)plane plane PRG - KRK
    2. Take the bus from Kraków, Dworzec Autobusowy MDA to Rymanówbus bus
    3. Drive from Rymanów to Medzilaborcecar car
    9h 39m
    €60–217

Prague to Medzilaborce by train

Calendar38Weekly Trains
Duration13h 7mAverage Duration
Ticket€45Cheapest Price
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Questions & Answers

Map of how to get from Prague to Medzilaborce.ExpandLaunch map view
  • Distance: 836.9 km
  • Duration: 13h 7m

What companies run services between Prague, Czechia and Medzilaborce, Presov, Slovakia?

You can take a train from Praha Hlavni Nadrazi to Medzilaborce Mesto via Kosice and Humenne in around 13h 7m. Alternatively, you can take a bus from Praha, ÚAN Florenc to Medzilaborce - SAD via Prešov, Prešov Station, and Humenné in around 14h 47m.

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