There are 9 ways to get from Prague to Mytilene by plane, train, bus, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis
best- Fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT)plane PRG - MJT
8h 25m€172–277Train to Vienna International Airport, fly to Mytilene International Airport Odysseas Elytis
cheapest- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Mytilene International Airport Odysseas Elytis (MJT)plane VIE - MJT
8h 54m€126–431Train, bus, ferry
- Take the train from Prague Main Train Station to Budapest Délitrain
- Take the bus from Budapest to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
32h 42m€164–324Bus, ferry via Sofia
- Take the bus from Praha, ÚAN Florenc to Sofia Central Bus Stationbus
- Take the bus from Sofia Central Bus Station to Kavala Central Bus Stationbus
- Take the ferry from Kavala to Mytileneferry Bsf
34h 10m€134–271Drive, car ferry
- Drive from Prague to Port of Ayvalikcar
- Take the carferry from Port of Ayvalik to Mytilenecarferry
21h 57m€335–472Fly Václav Havel Airport Prague to Chios Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to Chios Airport (JKH)plane PRG - JKH
- Take the ferry from Chios to Mytileneferry
16h 5m€127–420Fly Václav Havel Airport Prague to İzmir Adnan Menderes International Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to İzmir Adnan Menderes International Airport (ADB)plane PRG - ADB
- Take the ferry from Alsancak Limanı to Mytileneferry
8h 53m€138–365Bus, ferry
- Take the bus from Praha, ÚAN Florenc to Thessalonikibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
35h 14m€160–346Bus, ferry via Istanbul
- Take the bus from Prague Florenc Central Bus Station to Haskovo Central Bus Stationbus
- Take the bus from Haskovo Central Bus Station to Istanbul Büyük Otogaribus
- Take the bus from Istanbul Otogar to Ayvalikbus
- Take the ferry from Port of Ayvalik to Mytileneferry
39h 46m€271–316
Prague to Mytilene by bus, subway, foot, and ferry
Comparing Your Travel Options
The cheapest way to get from Prague to Mytilene is to bus and ferry which costs €160 - €350 and takes 35h 14m.
The fastest way to get from Prague to Mytilene is to fly which takes 8h 25m and costs €170 - €280.
The distance between Prague and Mytilene is 1588 km.
The best way to get from Prague to Mytilene without a car is to train and bus and ferry which takes 32h 42m and costs €160 - €330.
It takes approximately 8h 25m to get from Prague to Mytilene, including transfers.
Mytilene is 1h ahead of Prague. It is currently 12:00 PM in Prague and 1:00 PM in Mytilene.
There are 516+ hotels available in Mytilene.
What companies run services between Prague, Czechia and Mytilene, Greece?
Brussels Airlines, Sky Express, and four other airlines fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT) 3 times a day.
- Website
- en.aegeanair.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 11h 10m
- When
- Every day
- Estimated price
- €160–260
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 14h 38m
- When
- Every day
- Estimated price
- €110–370
Flights from Vienna International Airport to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 4h 20m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €100–420
- Website
- skyexpress.gr
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 9h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €90–320
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 5h 45m
- When
- Tuesday and Saturday
- Estimated price
- €160–260
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 9h 35m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–360
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Brussels
- Ave. Duration
- 9h 30m
- When
- Friday
- Estimated price
- €85–360
- Website
- transavia.com
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Amsterdam Schiphol
- Ave. Duration
- 8h 47m
- When
- Saturday
- Estimated price
- €130–600
- Website
- austrian.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport via Vienna International Airport
- Ave. Duration
- 5h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €80–310
Flights from Vienna International Airport to Mytilene International Airport Odysseas Elytis
- Ave. Duration
- 2h 5m
- When
- Monday
- Estimated price
- €95–400
- Website
- sunexpress.com
Flights from Václav Havel Airport Prague to İzmir Adnan Menderes International Airport
- Ave. Duration
- 2h 35m
- When
- Thursday and Sunday
- Estimated price
- €80–310
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Prague Main Train Station to Budapest Déli
- Ave. Duration
- 7h 13m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- 4 times a day
- Estimated price
- €19–35
- Website
- RegioJet
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 13m
- Frequency
- Every 4 hours
- Estimated price
- €35–55
- Website
- Czech Railways (ČD)
- Phone
- +302105233969
- [email protected]
- Website
- fptravel.gr
Bus from Budapest to Thessaloníki
- Ave. Duration
- 12h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- fptravel.gr
- Phone
- +359 88 949 0000
- [email protected]
- Website
- Union Ivkoni
Bus from Praha, ÚAN Florenc to Sofia Central Bus Station
- Ave. Duration
- 18h 6m
- Frequency
- Once a week
- Estimated price
- €45–85
- Website
- Union Ivkoni
- Phone
- +359 894 77 44 02
- [email protected]
- Website
- kaleiatravel.com
Bus from Sofia Central Bus Station to Kavala Central Bus Station
- Ave. Duration
- 6h
- Frequency
- 3 times a week
- Estimated price
- €30–50
- Schedules at
- en.kaleiatravel.com
- Phone
- +30 210 92 33 33
- [email protected]
- Website
- koronatravel.gr
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 23h 50m
- Frequency
- Once a week
- Estimated price
- €90
- Schedules at
- koronatravel.gr
- Phone
- +30-2310540970
- [email protected]
- Website
- Simeonidis Tours
Bus from Praha, ÚAN Florenc to Thessaloniki
- Ave. Duration
- 30h
- Frequency
- Once a week
- Estimated price
- €90–170
- Website
- Simeonidis Tours
- Phone
- +359 700 20 544
- Website
- Arda Tur
Bus from Prague Florenc Central Bus Station to Haskovo Central Bus Station
- Ave. Duration
- 23h 25m
- Frequency
- Once daily
- Estimated price
- €201
- Website
- Arda Tur
Bus from Haskovo Central Bus Station to Istanbul Büyük Otogari
- Ave. Duration
- 5h 45m
- Frequency
- 3 times a day
- Estimated price
- €44
- Website
- Arda Tur
- Phone
- +359 0885700870
- [email protected]
- Website
- Citylines
Bus from Haskovo Central Bus Station to Istanbul Büyük Otogari
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- €19–26
- Website
- Citylines
- Phone
- 0850 222 34 55
- Website
- MetroTurizm
Bus from Istanbul Otogar to Ayvalik
- Ave. Duration
- 8h 16m
- Frequency
- Once daily
- Estimated price
- €21–30
- Website
- MetroTurizm
- Standard
- €21–30
- Phone
- +30 21 0891 9800
- [email protected]
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Once a week
- Estimated price
- €70–180
- Website
- Blue Star Ferries
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 55m
- Frequency
- Once a week
- Estimated price
- €55–140
- Website
- Blue Star Ferries
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- Twice a week
- Estimated price
- €20–50
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Once a week
- Estimated price
- €70–180
- Website
- Blue Star Ferries
- Phone
- +90 266 331 49 49
- [email protected]
- Website
- ugurjalelines.com
Car ferry from Port of Ayvalik to Mytilene
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- €29–30
- Schedules at
- ugurjalelines.com
- Phone
- +30 210 89 19 800
- [email protected]
- Website
- Hellenic Seaways
Ferry from Chios to Mytilene
- Ave. Duration
- 3h
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- Hellenic Seaways
- Airplane Type Seats
- €35–50
- Phone
- 0 232 330 89 22
- [email protected]
- Website
- izdeniz.com.tr
Ferry from Alsancak Limanı to Mytilene
- Ave. Duration
- 2h
- Frequency
- Twice a week
- Estimated price
- €60
- Schedules at
- izdeniz.com.tr
- Phone
- 0545 783 50 61
- [email protected]
- Website
- jalemtur.com
Ferry from Port of Ayvalik to Mytilene
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- €30–40
- Schedules at
- jalemtur.com
Want to know more about travelling around Greece
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