There are 9 ways to get from Prague to Mytilene by plane, train, bus, ferry, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis
best- Fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT)plane PRG - MJT
7h 19m€142–267Bus, ferry via Sofia
cheapest- Take the bus from Praha, ÚAN Florenc to Sofia Central Bus Stationbus
- Take the bus from Sofia Central Bus Station to Kavala Central Bus Stationbus
- Take the ferry from Kavala to Mytileneferry Bsf
33h 40m€129–251Train, bus, ferry
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Budapest-Keletitrain Ec
- Take the bus from Budapest to Thessaloníkibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
33h 16m€180–406Drive, car ferry
- Drive from Prague to Port of Ayvalikcar
- Take the carferry from Port of Ayvalik to Mytilenecarferry
21h 57m€327–460Fly Václav Havel Airport Prague to Chios Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to Chios Airport (JKH)plane PRG - JKH
- Take the ferry from Chios to Mytileneferry
11h 5m€165–320Train to Vienna International Airport, fly to Mytilene International Airport Odysseas Elytis
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Mytilene International Airport Odysseas Elytis (MJT)plane VIE - MJT
8h 54m€145–417Fly Václav Havel Airport Prague to İzmir Adnan Menderes International Airport, ferry
- Fly from Václav Havel Airport Prague (PRG) to İzmir Adnan Menderes International Airport (ADB)plane PRG - ADB
- Take the ferry from Alsancak Limanı to Mytileneferry
8h 45m€138–295Bus, ferry
- Take the bus from Praha, ÚAN Florenc to Thessalonikibus
- Take the ferry from Thessaloniki to Mytileneferry Bsf
35h 14m€150–316Bus, ferry via Shumen
- Take the bus from Praga to Shumenbus
- Take the bus from Shumen to Bursabus
- Take the bus from Bursa to Ayvalıkbus
- Take the ferry from Port of Ayvalik to Mytileneferry
38h 40m€137–247
Prague to Mytilene by bus, subway, foot, and ferry
Questions & Answers
The cheapest way to get from Prague to Mytilene is to bus and ferry which costs €150 - €320 and takes 35h 14m.
The fastest way to get from Prague to Mytilene is to fly which takes 7h 19m and costs €140 - €270.
The distance between Prague and Mytilene is 1588 km.
The best way to get from Prague to Mytilene without a car is to train and bus and ferry which takes 33h 16m and costs €180 - €410.
It takes approximately 7h 19m to get from Prague to Mytilene, including transfers.
Mytilene is 1h ahead of Prague. It is currently 12:56 AM in Prague and 1:56 AM in Mytilene.
There are 581+ hotels available in Mytilene.
What companies run services between Prague, Czechia and Mytilene, Greece?
Brussels Airlines, Sky Express, and six other airlines fly from Václav Havel Airport Prague (PRG) to Mytilene International Airport Odysseas Elytis (MJT) twice daily.
- Website
- skyexpress.gr
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Athens
- Ave. Duration
- 8h 15m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €90–370
Flights from Václav Havel Airport Prague to Mytilene International Airport Odysseas Elytis via Thessaloniki
- Ave. Duration
- 4h 40m
- When
- Monday and Sunday
- Estimated price
- €95–310
Flights from Václav Havel Airport Prague to Chios Airport via Athens
- Ave. Duration
- 10h
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €110–420
Flights from Václav Havel Airport Prague to Chios Airport via Samos
- Ave. Duration
- 4h 35m
- When
- Monday
- Estimated price
- €110–370
Flights from Václav Havel Airport Prague to Chios Airport via Thessaloniki
- Ave. Duration
- 5h 5m
- When
- Monday
- Estimated price
- €110–360
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- Czech Railways (ČD)
- Phone
- +302105233969
- [email protected]
- Website
- fptravel.gr
Bus from Budapest to Thessaloníki
- Ave. Duration
- 12h 45m
- Frequency
- Twice a week
- Estimated price
- €60–90
- Schedules at
- fptravel.gr
- Phone
- +30 21 0891 9800
- [email protected]
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Twice a week
- Estimated price
- €60–150
- Website
- Blue Star Ferries
Ferry from Kavala to Mytilene
- Ave. Duration
- 7h 55m
- Frequency
- 3 times a week
- Estimated price
- €50–120
- Website
- Blue Star Ferries
Ferry from Chios to Mytilene
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a week
- Estimated price
- €18–45
- Website
- Blue Star Ferries
Ferry from Thessaloniki to Mytilene
- Ave. Duration
- 10h 5m
- Frequency
- Twice a week
- Estimated price
- €60–150
- Website
- Blue Star Ferries
Want to know more about travelling around Greece
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